Anti-HSPG2 Rat Monoclonal Antibody (CF640R) [clone: A7L6]

Proveedor: Biotium
BNC400315-500 BNC400315-100
BNC400315-500EA 560 EUR
BNC400315-500 BNC400315-100
Anti-HSPG2 Rat Monoclonal Antibody (CF640R) [clone: A7L6]
Anticuerpos
This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2).More Product Information
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