Anti-CD4 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: RPA-T4]

Proveedor: Tonbo Biosciences
20-0049-T500 20-0049-T100 20-0049-T025
20-0049-T500EA 285 EUR
20-0049-T500 20-0049-T100 20-0049-T025
Anti-CD4 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: RPA-T4]
Anticuerpos
The RPA-T4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17More Product Information
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