Anti-CASP9 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Proveedor: Bioss
BS-0050R-A555
BOSSBS-0050R-A555EA 876 EUR
BOSSBS-0050R-A555
Anti-CASP9 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Anticuerpos
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CASP9
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG1
Reactivity: Human
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