Anti-NLE1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Proveedor: Bioss
BS-12401R-A647
BOSSBS-12401R-A647EA 893 EUR
BOSSBS-12401R-A647
Anti-NLE1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Anticuerpos
The Notch signaling pathway is an evolutionary conserved system that is involved in intracellular communication. Notch receptors play an important role in development and cell-fate decisions. Notchless is a loss-of-function mutant allele that encodes for protein NLE1 (notchless homolog 1). NLE1 is a 485 amino acid WD40-repeat protein that binds to the cytoplasmic domain of Notch, regulating its signaling activity in Drosophila melanogaster and in mice. Deletion of the NLE1 gene in mice during the early stages of development results in embryonic death, while gene deletion in the late stagesMore Product Information
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