Anti-ABI1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Proveedor: Bioss
BS-1961R-A750
BOSSBS-1961R-A750EA 890 EUR
BOSSBS-1961R-A750
Anti-ABI1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anticuerpos
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation. Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac. In vitro, a trimeric complex of ABI1, EPS8 and SOS1 exhibits Rac specific guanine nucleotide exchange factor (GEF) activity and ABI1 seems to act as an adapter in the complex. Regulates ABL1/c-Abl-mediated phosphorylation of ENAH. Recruits WASF1 to lamellipodiaMore Product Information
Order Now

ESPECIFICACIONES

Nombre del antígeno ABI1
Environmentally Preferable
Sinónimos de antígenos Spectrin SH3 domain-binding protein 1|Abl-binding protein 4|SSH3BP|Eps8-binding protein|Eps8 SH3 domain-binding protein|Abl interactor 1|Nap1-binding protein|E3B1|Abelson interactor 1|SSH3BP1|ABLBP4|ABI1|NAP1BP|ABI-1
Tipo de anticuerpo Primario
Clonalidad Polyclonal
Conjugado Alexa Fluor® 750
Reactividad Rat
Huésped Rabbit
ID del gen 10006
Isotipo IgG
Western blot Yes
InmunoQuímica Yes
FluorescenciaInmunológica Yes
Modificación Unmodified
Epítopo 101-200/508
Inmunógeno KLH conjugated synthetic peptide derived from human ABI1
Forma Liquid
Molecular weight 55 kDa
Purification Purified by Protein A
Concentración 1 µg/µl
Storage buffer Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Temperatura de almacenamiento Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Shipping temperature 4 °C
Tested applications ICC

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Más About VWR