Anti-PLEKHM1 Rabbit Polyclonal Antibody

Proveedor: Bioss
BS-8062R
BOSSBS-8062REA 725 EUR
BOSSBS-8062R
Anti-PLEKHM1 Rabbit Polyclonal Antibody
Anticuerpos
Involved in vesicular transport in the osteoclast (By similarity). May have a role in sialyl-lex-mediated transduction of apoptotic signals.Tissue specificity: Expressed in placenta, liver, prostate, thymus, spleen, ovary, colon, colon carcinoma and peripheral blood lymphocytes (PBL). Weakly expressed in brain, lung, kidney, and testis. No expression in heart, skeletal muscle, pancreas and small intestine. Predominantly expressed in the breast carcinoma cell line MCF-7.Involvement in disease:Defects in PLEKHM1 are the cause of osteopetrosis autosomal recessive type 6 (OPTB6); also known asMore Product Information
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