Anti-Cullin 7 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Proveedor: Bioss
BS-9127R-A680
BOSSBS-9127R-A680EA 893 EUR
BOSSBS-9127R-A680
Anti-Cullin 7 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Anticuerpos
Component of a probable SCF-like E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity). Seems not to promote polyubiquitination and proteasomal degradation of TP53. in vitro, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity.Involvement in disease: Defects in CUL7 are the cause of 3M syndrome type 1 (3M1). An autosomal recessive disorderMore Product Information
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