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Image Unavailable-CAYM16455-10

Malonyl coenzyme A lithium salt ≥90%

Descripción: Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.
Numero del catalogo: CAYM16455-10
UOM: 1 * 10 mg
Proveedor: Cayman Chemical
Image Unavailable-07441-10MG

Supelco® Organic Reference Standard, Malonyl-L-Carnitine Lithium Salt

Descripción: Organic Standard, Malonyl-ʟ-carnitine lithium salt
Numero del catalogo: 07441-10MG
UOM: 1 * 10 mg
Proveedor: Merck
Image Unavailable-CAYM10005647-5

Cerulenin ≥98%, crystalline solid

Descripción: A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.
Numero del catalogo: CAYM10005647-5
UOM: 1 * 5 mg
Proveedor: Cayman Chemical
Image Unavailable-BOSSBS-12952R-A680

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Descripción: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Numero del catalogo: BOSSBS-12952R-A680
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-12954R-A680

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Descripción: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Numero del catalogo: BOSSBS-12954R-A680
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-12952R-A750

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Descripción: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Numero del catalogo: BOSSBS-12952R-A750
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-12954R-A750

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Descripción: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Numero del catalogo: BOSSBS-12954R-A750
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-APOSBIC7401-100MG

Coenzyme A trilithium salt

Descripción: Coenzyme A trilithium salt
Numero del catalogo: APOSBIC7401-100MG
UOM: 1 * 100 mg
Proveedor: Apollo Scientific

Certificados


Image Unavailable-CAYM10547-5

4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Descripción: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder
Numero del catalogo: CAYM10547-5
UOM: 1 * 5 mg
Proveedor: Cayman Chemical
Image Unavailable-CAYM21722-10

Coenzyme A sodium salt hydrate ≥95%

Descripción: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.
Numero del catalogo: CAYM21722-10
UOM: 1 * 10 mg
Proveedor: Cayman Chemical
Image Unavailable-19533-5MG

Supelco® Organic Reference Standard, Geranyl Pyrophosphate Lithium Salt

Descripción: Organic Standard, Geranyl pyrophosphate lithium salt
Numero del catalogo: 19533-5MG
UOM: 1 * 5 mg
Proveedor: Merck
Image Unavailable-73885-10MG

Supelco® Organic Reference Standard, D-2-Phosphoglyceric Acid Lithium Salt

Descripción: Organic Standard, ᴅ-2-Phosphoglyceric acid lithium salt
Numero del catalogo: 73885-10MG
UOM: 1 * 10 mg
Proveedor: Merck
Image Unavailable-89163-1MG

Supelco® Organic Reference Standard, (±)-Mevalonic acid-(methyl-d₃) lithium salt

Descripción: Organic Standard, (±)-Mevalonic acid-(methyl-d₃) lithium salt
Numero del catalogo: 89163-1MG
UOM: 1 * 1 mg
Proveedor: Merck
Image Unavailable-89921-50MG

Supelco® Organic Reference Standard, (±)-2,4-Dihydroxybutyric acid lithium salt

Descripción: Organic Standard, (±)-2,4-Dihydroxybutyric acid lithium salt
Numero del catalogo: 89921-50MG
UOM: 1 * 50 mg
Proveedor: Merck
Image Unavailable-55385-10MG

Supelco® Organic Reference Standard, 3-Phosphoshikimic acid lithium salt

Descripción: Organic Standard, 3-Phosphoshikimic acid lithium salt
Numero del catalogo: 55385-10MG
UOM: 1 * 10 mg
Proveedor: Merck
Image Unavailable-04609-50MG

Supelco® Organic Reference Standard, O-Succinyl-ʟ-Carnitine Lithium Salt

Descripción: Organic Standard, O-Succinyl-ʟ-carnitine lithium salt
Numero del catalogo: 04609-50MG
UOM: 1 * 50 mg
Proveedor: Merck
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