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Numero del catalogo: (BOSSBS-1347R-A647)

Proveedor: Bioss

Descripción: Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-13481R-A350)

Proveedor: Bioss

Descripción: The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been designated RET-II and PTC5. [provided by RefSeq, Feb 2010].

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-0762R-CY3)

Proveedor: Bioss

Descripción: Midnolin

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-2302R-A350)

Proveedor: Bioss

Descripción: Catalase is the classical marker for peroxisomes and is the most abundant protein within peroxisomes. It is found in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-2302R-A488)

Proveedor: Bioss

Descripción: Catalase is the classical marker for peroxisomes and is the most abundant protein within peroxisomes. It is found in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-6159R-A350)

Proveedor: Bioss

Descripción: This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-2440R-A350)

Proveedor: Bioss

Descripción: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1, thus stimulating the kinase activity and intensive autophosphorylation of IRAK1. Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1. Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex. In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation. Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation. Phosphorylates NCF1 and regulates NADPH oxidase activation after LPS stimulation suggesting a similar mechanism during microbial infections.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-0762R-A647)

Proveedor: Bioss

Descripción: Midnolin

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-0761R-FITC)

Proveedor: Bioss

Descripción: May be involved in regulation of genes related to neurogenesis in the nucleolus.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-6159R-CY3)

Proveedor: Bioss

Descripción: This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-0762R-CY5)

Proveedor: Bioss

Descripción: Midnolin

UOM: 1 * 100 µl

Promoción

Proveedor: Tonbo Biosciences

Descripción: The MP4-25D2 antibody is specific for human IL-4, a pleiotropic cytokine that Th2 cell differentiation, B cell proliferation and differentiation, and B cell class switching to IgE. MP4-25D2 is a neutralizing antibody and is reported to cross react with rhesus monkey IL-4.

Proveedor: Tonbo Biosciences

Descripción: The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

Numero del catalogo: (BOSSBS-0317R)

Proveedor: Bioss

Descripción: Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-1308R)

Proveedor: Bioss

Descripción: Anti-XAF1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-1668R)

Proveedor: Bioss

Descripción: Anti-XBP1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Promoción