Anti-LRRC32 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: GARP5]

Proveedor: Tonbo Biosciences
20-9882-T100 20-9882-T025
20-9882-T100EA 264 EUR
20-9882-T100 20-9882-T025
Anti-LRRC32 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: GARP5]
Anticuerpos
The GARP5 antibody reacts with human GARP, also known as LRRC32 or Garpin, an 80 kDa transmembrane protein which acts as a receptor for the latent form of TGF-beta 1 (pro-TGF-beta), preventing its secretion. Specifically, GARP is reported to associate with the pro-domain of TGF-beta 1, known as latency-associated peptide (LAP), which must be cleaved to release the biologically active cytokine. The putative role of GARP in sequestering the TGF-beta is important for regulating its activity, as TGF-beta signaling is involved in development and function of Th17, Treg and many other immune cellMore Product Information
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