Anti-CD274 Rat Monoclonal Antibody [clone: 10F.9G2]

Proveedor: Tonbo Biosciences
40-1243-U500 40-1243-U100
40-1243-U500EA 176 EUR
40-1243-U500 40-1243-U100
Anti-CD274 Rat Monoclonal Antibody [clone: 10F.9G2]
Anticuerpos
The 10F.9G2 antibody is specific for mouse CD274, more commonly known as PD-L1 or B7-H1, which acts as a ligand for the T cell co-regulatory receptor PD-1 (CD279). This interaction modulates T cell antigen receptor (TCR) signaling and therefore T cell activation. PD-L1 binding to PD-1 expressed on CD4- CD8- thymocytes participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-L1 may also bind PD-1 following the receptor’s inducible expression on activated, mature T cells, where it has been proposed to limit T cell activation.More Product Information
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