S. aureus (Cowan strain) Protein A, MP Biomedicals
Proveedor: MP Biomedicals
Protein A is a highly stable surface receptor which is capable of binding the Fc portion of immunoglobulins, especially IgGs, from a large number of species. Each protein A molecule can bind 2 molecules of IgG, allowing the formation of a precipitate.
- Binding capacity: ~9 to 11 mg of human IgG per mg solid
- Extinction Coefficient (E1%): E1%280 = 1,4
- Isoelectric point (pI): 4,85 to 5,10
It may be coupled to a wide variety of reporter molecules including fluorescent dyes, enzyme markers, biotin, colloidal gold and radioactive iodine without affecting the antibody binding site. These conjugates may be used to track immunoglobulins in histochemical, western and ELISA applications. It may be immobilised onto a solid support to facilitate the purification and recovery of either polyclonal or monoclonal immunoglobulins.
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