Anti-HIF1A Mouse Monoclonal Antibody (CF680) [clone: HIF1A-84]

Proveedor: Biotium
BNC800084-500 BNC800084-100
BNC800084-500EA 560 EUR
BNC800084-500 BNC800084-100
Anti-HIF1A Mouse Monoclonal Antibody (CF680) [clone: HIF1A-84]
Anticuerpos
HIF1 (hypoxia-inducible factor 1), a heterodimeric transcription factor complex central to cellular response to hypoxia, consists of two subunits (HIF-1 alpha and HIF-1 beta) which are basic helix-loop-helix proteins of the PAS (Per, ARNT, Sim) family. Expression of HIF-1 alpha protein is regulated by cellular oxygen level alterations as well as in oxygen-independent manner via different cytokines (through the PI3K-AKT-mTOR pathway), growth factors, oncogenic activation, or loss of tumor suppressor function etc. In normoxic cells, HIF-1 alpha is proline hydroxylated leading to aMore Product Information
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