Anti-TIMP3 Rabbit Polyclonal Antibody (Purified) [clone: Rabbit PAb]

Proveedor: Biotium
BNUB0408-500 BNUB0408-100
BNUB0408-500EA 511 EUR
BNUB0408-500 BNUB0408-100
Anti-TIMP3 Rabbit Polyclonal Antibody (Purified) [clone: Rabbit PAb]
Anticuerpos
TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

Type: Primary
Antigen: TIMP3
Clonality: Polyclonal
Clone: Rabbit PAb
Conjugation: Purified
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Cow, Dog, Horse, Human, Mouse, Rat
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