Anti-NKX2-1 Mouse Monoclonal Antibody (Biotin) [clone: 8G7G3/1]

Proveedor: Biotium
BNCB0448-500 BNCB0448-100
BNCB0448-500EA 560 EUR
BNCB0448-500 BNCB0448-100
Anti-NKX2-1 Mouse Monoclonal Antibody (Biotin) [clone: 8G7G3/1]
Anticuerpos
Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.

Type: Primary
Antigen: NKX2-1
Clonality: Monoclonal
Clone: 8G7G3/1
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse, Rat
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Más About VWR