Anti-CD66 molecule Mouse Monoclonal Antibody (Purified) [clone: CEA31]

Proveedor: Biotium
BNUB0670-500 BNUB0670-100
BNUB0670-500EA 511 EUR
BNUB0670-500 BNUB0670-100
Anti-CD66 molecule Mouse Monoclonal Antibody (Purified) [clone: CEA31]
Anticuerpos
This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA ) from pleural mesotheliomas (rarely or weakly CEA ). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Type: Primary
Antigen: CD66 molecule
Clonality: Monoclonal
Clone: CEA31
Conjugation: Purified
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Monkey
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