Anti-CPS1 Mouse Monoclonal Antibody (CF405S) [clone: CPS1/1022]

Proveedor: Biotium
BNC041022-500 BNC041022-100
BNC041022-500EA 560 EUR
BNC041022-500 BNC041022-100
Anti-CPS1 Mouse Monoclonal Antibody (CF405S) [clone: CPS1/1022]
Anticuerpos
This MAb recognizes a protein of 165 kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomasMore Product Information
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