Gestrinone ≥98%, crystalline solid

Proveedor: Cayman Chemical

10006488-100 10006488-500 10006488-1
CAYM10006488-100EA 161 EUR
CAYM10006488-100 CAYM10006488-500 CAYM10006488-1
Gestrinone ≥98%, crystalline solid
Gestrinone

Gestrinone is a synthetic steroid used occasionally to treat endometriosis.


Endometriosis is common disease characterised by the presence of endometrial tissue outside the uterus which affects approximately 10% of premenopausal women. Gestrinone acts centrally on the hypothalamic-pituitary system to suppress release of lutenizing hormone (LH) and follicle-stimulating hormone (FSH), thus reducing estrogen synthesis. It also binds to androgen (AR), progesterone (PR), and estrogen (ER) receptors in the human endometrial tissue but not to steroid hormone binding globulin or corticord-binding globulin. Gestrinone binds to AR and PR with EC50 values of approximately 20 and 30 nM, respectively. These values reflect approximately 5 – 6 fold lower affinity than testosterone and progesterone, the natural AR and PR ligands, for these receptors.

Formula: C₂₁H₂₄O₂
Número MDL: MFCD00865561
Núm. CAS: 16320-04-0

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Resultados test especificaciones

Purity ≥98%
Formulation Crystalline solid
λmax 238, 341 nm
Storage −20 °C
Stability ≥2 years


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