Colato de sodio ≥98.5%, white powder

Proveedor: MP Biomedicals

Sinónimos: 3alpha,7alpha,12alpha-Trihidroxi-5beta-colanoato de sodio, 3α,7α,12α-Trihidroxi-5β-colanoato de sodio, Ácido 3α,7α,12α-trihidroxi-5β-colan-24-oico

02102897.5 0210289705 02102897.1 02102897.3 0210289701
ICNA02102897.5EA 636 EUR
ICNA02102897.5 ICNA0210289705 ICNA02102897.1 ICNA02102897.3 ICNA0210289701
Colato de sodio ≥98.5%, white powder
Colato de sodio

Cholic acid is a biochemical solubilizing agent (a non-ionic, non-denaturing detergent). Occurs inconjugation with glycine or taurine in bile of most vertebrates.


  • Critical Micelle Concentration (CMC): 14mM


Cholic acid is used in the solubilization of membrane-bound proteins in their native state. It is a component for the preparation of liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.
Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes.


Cholic acid is a biochemical solubilising agent (a non-ionic, non-denaturing detergent). Occurs inconjugation with glycine or taurine in bile of most vertebrates.


Soluble in water (100 mg/ml). Soluble in ethanol (40 mg/ml - clear, colorless solution).

Formula: C₂₄H₃₉NaO₅
MW: 430,56 g/mol
Pto. de fusión: 198 °C
Temperatura de almacenaje: Ambiente
Número MDL: MFCD00150749
Núm. CAS: 361-09-1
EINECS: 206-643-5

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Resultados test especificaciones

Identity Test Passes
Purity (HPLC) ≥98,5%
Loss on Drying ≤5%
pH (2% aq soln) 7,5 - 9,0
Solubility (2% aq soln) Clear and Colorless
Sodium Deoxycholate ≤1,5%
Heavy Metals ≤50 ppm

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