Colato de sodio ≥98.5%, white powder
Proveedor: MP Biomedicals
Sinónimos:
3alpha,7alpha,12alpha-Trihidroxi-5beta-colanoato de sodio, 3α,7α,12α-Trihidroxi-5β-colanoato de sodio, Ácido 3α,7α,12α-trihidroxi-5β-colan-24-oico
Cholic acid is a biochemical solubilizing agent (a non-ionic, non-denaturing detergent). Occurs inconjugation with glycine or taurine in bile of most vertebrates.
- Critical Micelle Concentration (CMC): 14mM
Cholic acid is used in the solubilization of membrane-bound proteins in their native state. It is a component for the preparation of liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.
Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes.
Cholic acid is a biochemical solubilising agent (a non-ionic, non-denaturing detergent). Occurs inconjugation with glycine or taurine in bile of most vertebrates.
Soluble in water (100 mg/ml). Soluble in ethanol (40 mg/ml - clear, colorless solution).
Formula:
C₂₄H₃₉NaO₅ MW: 430,56 g/mol Pto. de fusión: 198 °C Temperatura de almacenaje: Ambiente |
Número MDL:
MFCD00150749 Núm. CAS: 361-09-1 EINECS: 206-643-5 |
Resultados test especificaciones
Identity Test | Passes |
Purity (HPLC) | ≥98,5% |
Loss on Drying | ≤5% |
pH (2% aq soln) | 7,5 - 9,0 |
Solubility (2% aq soln) | Clear and Colorless |
Sodium Deoxycholate | ≤1,5% |
Heavy Metals | ≤50 ppm |
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