Mirin ≥95% (by TLC)

Proveedor: ENZO LIFE SCIENCES

BMLGR3570005 BMLGR3570025
ENZOBMLGR3570005EA 110 EUR
ENZOBMLGR3570005 ENZOBMLGR3570025
Mirin ≥95% (by TLC)
Mirin

MRN inhibitor


The MRN-ATM pathway is essential for sensing the signaling from DNA double-strand breaks. Mirin is an inhibitor of MRN discovered using a forward chemical genetic screen. It prevents MRN-dependent activation of ATM without affecting ATM protein kinase activity and it inhibits Mre11-associated exonuclease activity. IC50=66µM. It abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.

Formula: C₁₀H₈N₂O₂S
Número MDL: MFCD05885480
Núm. CAS: 299953-00-7
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=af949578994c2f4bc6ee2ddfee789e4b23dd32e5&vid=b0b162e39e14c207920bb1c7f325c3cc93a46895&prid=web&clid=SAPDAM

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