MK-886 ≥98% (by HPLC)
Proveedor: ENZO LIFE SCIENCES
BMLEI2660005
BMLEI2660025
ENZOBMLEI2660005EA
110
EUR
ENZOBMLEI2660005
ENZOBMLEI2660025
MK-886 ≥98% (by HPLC)
MK-886
Inhibitor of PPARα activation. Inhibits 5-lipoxygenase-activating protein (FLAP) and leukotriene biosynthesis. Binds to FLAP with high affinity and prevents the activation of 5-lipoxygenase. IC50’s for leukotriene biosynthesis: 2.5 nM in intact leukocytes; 1.1 µM in whole blood. Induces apoptosis through the mitochondrial pathway.
- FLAP inhibitor
White solid.
Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml).
Formula:
C₂₇H₃₃ClNO₂S·Na Temperatura de almacenaje: Ambiente |
Número MDL:
MFCD00876710 Núm. CAS: 118414-82-7 |
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