Human Recombinant TGF-beta 2

Proveedor: STEMCELL Technologies

78174 78174.1
STMC78174EA 184 EUR
STMC78174 STMC78174.1
Human Recombinant TGF-beta 2
Proteínas y Péptidos

Transforming growth factor (TGF) beta 2 is a member of the TGF-β superfamily and regulates diverse cellular phenotypes. Similar to TGF-β1 and -β3, TGF-β2 signals via serine-threonine kinase type I and II receptors and activates signal transduction via SMAD family proteins, regulating a variety of functions such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism (de Caestecker; Massague; Zuniga et al.). TGF-β2 is important in many developmental processes; for example, mice with TGF-β2 deletions show defects in the development of cardiac, lung, craniofacial, limb, eye, ear, and urogenital systems (Dunker and Kreiglstein).


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