Rabbit monoclonal IgG antibody against SARS-CoV, SARS-CoV-2 (2019-nCoV) nucleoprotein (HEK293-expressed recombinant).
The Anti-SARS-CoV Nucleoprotein Antibody, Clone 001 (Recombinant) reacts with the nucleoprotein expressed by SARS-associated coronavirus (SARS-CoV) and has shown to cross-react with SARS-CoV-2 (2019-nCoV). Coronaviruses infect both animal and human hosts and can cause a wide range of potentially fatal symptoms, including upper respiratory tract infections in humans. These viruses are enveloped and contain single-stranded RNA associated with a nucleoprotein. These nucleoproteins are abundantly produced within CoV-infected cells, where their primary function is to package the viral genome into flexible, helical ribonucleoprotein complexes called nucleocapsids. The nucleocapsid binds to genomic RNA and is understood to interact with viral membrane proteins during virion assembly, therefore playing a critical role in ensuring the efficiency of viral transcription, translation, and assembly. In host cells, the nucleocapsid can directly impact normal cell functions and cause cell-cycle deregulation, increased COX-2 production, and inhibition of interferon production.
Precaución: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').
Type:
Antigen: SARS-CoV Nucleoprotein
Clonality: Monoclonal
Clone: 001
Conjugation:
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity:
