Human Recombinant IL-7 (CTGrade GMP) (from E. coli)

Proveedor: Shenandoah Biotechnology

500-07-100UG 500-07-1MG 500-07-50UG
SHBT500-07-100UGEA 1840 EUR
SHBT500-07-100UG SHBT500-07-1MG SHBT500-07-50UG
Human Recombinant IL-7 (CTGrade GMP) (from E. coli)
Proteínas y Péptidos

IL-7 promotes the stimulation of multipotent (pluripotent) hematopoietic stem cells into lymphoid progenitor cells. IL-7, along with IL-2, 15, and 21, is a member of the common gamma (γc) chain cytokine family.


  • High Quality
  • Low Endotoxin
  • Lot-to-lot Consistency
  • Animal Free
  • Manufactured following GMP guidelines


Secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. Signals through its receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and natural killer cells. Is a regulator of intestinal mucosal lymphocyte proliferation. Promotes favorable phenotypes in adoptive cellular therapies such as CAR-T cell therapy when combined with IL-15. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.


Host cell Protein: ≤30 ng/ml
Host cell DNA: ≤0,01 ng/ml
Sterility testing: No growth
Mycoplasma: Negative


Precaución: For research use or further manufacturing only.

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ESPECIFICACIONES

Nombre de proteína / péptido IL-7
Environmentally Preferable
Sinónimos de proteínas Lymphopoietin 1 (LP-1)|pre-B cell Factor
Tipo de proteína / péptido Recombinant
Función de la proteína Cytokine
Especies Human
Fuente E. coli
Conjugado Unconjugated
ID del gen P13232
Sequence MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
Sin proteasa N
Libre de animales Y
Sin nucleasas N
Sin transportista Y
Sin endotoxina N
Nivel de endotoxina Low
Contenido de endotoxinas Endotoxin LAL (EU/µg) ≤0,05
Actividad biológica Bioactivity assay: Proliferation using PHA-activated PBMC, ED50 ≤0,5 ng/ml, Bioactivity ≥1,2x10⁵ IU/µg
Pureza ≥97%
Grado CTGrade GMP
Formulación 20 mM sodium phosphate, pH 7,5
Molecular weight 17,5 kDa
Instrucciones de reconstitución Sterile water at 0.1 - 0.5 mg/ml
Condiciones de almacenamiento At or below –20 °C
Shipping temperature Ambient
Tested applications Bioassay

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