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T4 UvsX DNA Recombinase

Proveedor: G-Biosciences

Descripción: T4 UvsX DNA recombinase mediates DNA strand exchange between homologous chromosomes. The protein forms a right-handed nucleoprotein complex on single ssDNA called the presynaptic filament that can search for homology in duplex DNA and pair the recombining DNA molecules to form a DNA joint molecule. This process is aided by ssDNA binding proteins and recombination mediators. The filament is then elongated by DNA polymerase with the newly synthesised strand displacing the old strand. The newly synthesised duplex DNA can then act as a template for the next cycle to achieve exponential amplification of dsDNA. <i>E.coli</i> cells expressing recombinant T4 UvsX gene.

Anti-IFNG Rat Monoclonal Antibody (FITC (Fluorescein)) [clone: XMG1.2]

Proveedor: Tonbo Biosciences

Descripción: The XMG1.2 antibody is specific for mouse Interferon-gamma (IFN-g), a 20 kDa type II cytokine known for its central roles in protection against bacterial or viral pathogens and for its anti-tumor properties. IFN-g is secreted by several types of immune cells, which allow the cytokine to modulate innate immunity, when secreted by NK and NKT cells, and to function in supporting adaptive immunity when secreted by Th1 and CD8+ T cells (CTLs).

Anti-MHC II (I-A/I-E) Rat Monoclonal Antibody (FITC (Fluorescein)) [clone: M5/115.15.2]

Proveedor: Tonbo Biosciences

Descripción: The M5/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7.

Anti-IFNG Rat Monoclonal Antibody (violetFluor® 450) [clone: XMG1.2]

Proveedor: Tonbo Biosciences

Anti-CD252 (OX40 Ligand) Rat Monoclonal Antibody (APC (Allophycocyanine)) [clone: RM134L]

Proveedor: Tonbo Biosciences

Descripción: The RM134L antibody recognizes CD252, also known as OX-40 Ligand or CD134 Ligand, a member of the TNF superfamily that is present on the surface of antigen presenting cells and activated B lymphocytes. The OX-40 Ligand interacts with OX-40 (CD134) which is expressed primarily on activated T cells. This costimulatory interaction leads to increased proliferation and IL-2 production responses of activated T cells, and at the same time enhances proliferation and immunoglobulin secretion by activated B cells.