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Descripción: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Numero del catalogo: BOSSBS-10239R-A350
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Numero del catalogo: BOSSBS-10239R-A488
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Numero del catalogo: BOSSBS-10216R-A350
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: 2,2'-Bis(hydroxymethyl)diphenyl ether ≥98.0% (por GC)
Numero del catalogo: TCIAB1643-1G
UOM: 1 * 1 g
Proveedor: TCI


Descripción: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Numero del catalogo: BOSSBS-10216R-A555
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Inhibits ergosterol biosynthesis at the level of squalene epoxidase. Potent non-competitive inhibitor of squalene epoxidase from Candida (Ki=30 nM), inhibiting mammalian enzymes at higher concentrations (4-77 µM). It inhibits HUVEC proliferation and angiogenesis and displays interesting anti-inflammatory and free radical scavenging activities. Clinically useful antifungal agent.
Numero del catalogo: ENZOBMLEI3180100
UOM: 1 * 100 mg
Proveedor: ENZO LIFE SCIENCES


Descripción: Metallothioneins (MTs) are a class of ubiquitous, low molecular weight, cysteine-rich, metal binding proteins that function in the metabolism of zinc and copper. MT protects against exposure to toxic metals such as mercury and cadmium as well as a variety of other stress conditions. There are four mammalian MT isoforms: MT-I, -II, -III, -IV, each of which is encoded by individual genes. MT expression is induced by heavy metal cations, starvation, elevated temperature, lipopolysaccharide, inflammatory cytokines, free radicals, and ionizing radiation.
Numero del catalogo: ENZOADISPA550F
UOM: 1 * 200 µG
Proveedor: ENZO LIFE SCIENCES


Descripción: (-)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane 96%
Numero del catalogo: APOSOR8725-25G
UOM: 1 * 25 g
Proveedor: Apollo Scientific


Descripción: Reagent for aluminium. Aurintricarboxylic acid readily polymerises in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca²⁺ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca²⁺-activated protease that is activated during apoptosis.
Numero del catalogo: A36883-25G
UOM: 1 * 25 g
Proveedor: SIGMA ALDRICH MICROSCOPY


Descripción: (+)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane ≥97.0% (by HPLC)
Numero del catalogo: TCIAB2048-5G
UOM: 1 * 5 g
Proveedor: TCI


Descripción: (R)-(+)-2,2'-Bis(difenilfosfino)-1,1'-binaftilo 97%
Numero del catalogo: APOSOR43631-5G
UOM: 1 * 5 g
Proveedor: Apollo Scientific


Descripción: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Numero del catalogo: BOSSBS-5164R
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. catalyses the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. hydrolyses 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Numero del catalogo: BOSSBS-5164R-A680
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
Numero del catalogo: BOSSBS-5164R-CY5
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: (-)-4,5-Bis[hydroxy(diphenyl)methyl]-2,2-dimethyl-1,3-dioxolane ≥97.0% (by HPLC)
Numero del catalogo: TCIAB1614-1G
UOM: 1 * 1 g
Proveedor: TCI


Descripción: (S)-(-)-2,2'-Bis(difenilfosfino)-1,1'-binaftilo
Numero del catalogo: APOSOR54464-100G
UOM: 1 * 100 g
Proveedor: Apollo Scientific