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Image Unavailable-BOSSBS-3216R-A680

Anti-HDAC7 Ser358 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numero del catalogo: (BOSSBS-3216R-A680)
Proveedor: Bioss
Descripción: HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localised mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyses removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11261R-A488

Anti-STX6 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Numero del catalogo: (BOSSBS-11261R-A488)
Proveedor: Bioss
Descripción: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11261R-A680

Anti-Syntaxin 6 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numero del catalogo: (BOSSBS-11261R-A680)
Proveedor: Bioss
Descripción: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalisation upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11261R-CY7

Anti-STX6 Rabbit Polyclonal Antibody (Cy7®)

Numero del catalogo: (BOSSBS-11261R-CY7)
Proveedor: Bioss
Descripción: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11261R-FITC

Anti-STX6 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numero del catalogo: (BOSSBS-11261R-FITC)
Proveedor: Bioss
Descripción: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.
UOM: 1 * 100 µl
Image Unavailable-EDQMY0001168

Organic reference standards, potassium clavulanate, Ph. Eur., RS

Numero del catalogo: (EDQMY0001168)
Proveedor: EDQM
Descripción: Organic Standard, Potassium clavulanate impurity G, 4-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-4-oxobutanoic acid (N-(hydrogensuccinyl)tyrosine)
UOM: 1 * 5 mg
Product Image-PRSI7437P

Human ESR1 peptide

Numero del catalogo: (PRSI7437P)
Proveedor: ProSci Inc.
Descripción: 18 amino acids near the carboxy terminus of ESR1.
UOM: 1 * 50 µG
Product Image-PRSI7289P

Human ERRF2 peptide

Numero del catalogo: (PRSI7289P)
Proveedor: ProSci Inc.
Descripción: 15 amino acids near the carboxy terminus of human ERRF2.
UOM: 1 * 50 µG
Product Image-PRSI7309P

Human KANK2 peptide

Numero del catalogo: (PRSI7309P)
Proveedor: ProSci Inc.
Descripción: 16 amino acids near the carboxy terminus of human KANK2.
UOM: 1 * 50 µG
Image Unavailable-PRSI7263P

Human KREMEN2 peptide

Numero del catalogo: (PRSI7263P)
Proveedor: ProSci Inc.
Descripción: 15 amino acids near the carboxy terminus of human KREMEN2.
UOM: 1 * 50 µG
Image Unavailable-PRSI4415P

Human TBC1D4 peptide

Numero del catalogo: (PRSI4415P)
Proveedor: ProSci Inc.
Descripción: 19 amino acids near the carboxy terminus of human TBC1D4.
UOM: 1 * 50 µG
Image Unavailable-PRSI4445P

Human RIM2 peptide

Numero del catalogo: (PRSI4445P)
Proveedor: ProSci Inc.
Descripción: 16 amino acids near the carboxy terminus of human RIM2.
UOM: 1 * 50 µG
Image Unavailable-PRSI7391P

Human AKT1S1 peptide

Numero del catalogo: (PRSI7391P)
Proveedor: ProSci Inc.
Descripción: 19 amino acids near the carboxy terminus of human AKT1S1.
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-2835R-A350

Anti-ASB2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numero del catalogo: (BOSSBS-2835R-A350)
Proveedor: Bioss
Descripción: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7533R-CY5

Anti-LPIN1 Rabbit Polyclonal Antibody (Cy5®)

Numero del catalogo: (BOSSBS-7533R-CY5)
Proveedor: Bioss
Descripción: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7533R-A555

Anti-LPIN1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numero del catalogo: (BOSSBS-7533R-A555)
Proveedor: Bioss
Descripción: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
UOM: 1 * 100 µl
Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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