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Numero del catalogo: (PRSI26-672)
Proveedor: ProSci Inc.
Descripción: The specific function of RDHE2 is not yet known.RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).
UOM: 1 * 50 µG


Numero del catalogo: (PRSI50-201)
Proveedor: ProSci Inc.
Descripción: DARPP-32 is a dopamine (DA) and cAMP-regulated ~32k phosphoprotein that is associated with dopaminoceptive neurons (Fienberg et al., 1998). The protein inhibits Protein Phosphatase I when it is phosphorylated on Thr34. In contrast, when DARPP-32 is phosphorylated on Thr75 the protein acts as an inhibitor of PKA (Bibb et al., 1999). Phosphorylation of DARPP-32 is thought to play a critical role in the regulation of dopaminergic neurotransmission. In addition, the activity of DARPP-32 is also thought to play important roles
in the actions of alcohol, caffeine and Prozac® (Maldve et al., 2002; Lindskog et al., 2002; Svenningsson et al., 2002).
UOM: 1 * 100 µl


Proveedor: Alcoholes Montplet
Descripción: Etanol desnaturalizado al 70%
Proveedor: MERCK PRODUCTION CHEMICALS
Descripción: Alcohol polivinílico 18-88, EMPROVE® EXPERT JPE, Ph. Eur., USP suitable for use as excipient, SAFC®

FDS

Proveedor: MERCK PRODUCTION CHEMICALS
Descripción: Alcohol polivinílico 5-88, EMPROVE® EXPERT Ph. Eur., USP, JPE suitable for use as excipient, SAFC®

FDS

Proveedor: MERCK PRODUCTION CHEMICALS
Descripción: Alcohol polivinílico, M.W. 115,000 ≥88%, EMPROVE® EXPERT Ph. Eur., USP, JPE suitable for use as excipient, hydrolysed, SAFC®

FDS

Proveedor: MERCK PRODUCTION CHEMICALS
Descripción: Alcohol polivinílico 26 - 88, EMPROVE® EXPERT Ph. Eur., USP, JPE suitable for use as excipient, hydrolysed, SAFC®

FDS

Proveedor: MERCK PRODUCTION CHEMICALS
Descripción: Alcohol polivinílico, M.W. 27,000 ≥98%, EMPROVE® EXPERT JPE suitable for use as excipient, hydrolysed, SAFC®

FDS

Numero del catalogo: (PRSI50-180)
Proveedor: ProSci Inc.
Descripción: The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002; Wenthold et al., 2003; Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989; Alvestad et al., 2003; Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
UOM: 1 * 50 µl


Numero del catalogo: (PRSI50-181)
Proveedor: ProSci Inc.
Descripción: The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002; Wenthold et al., 2003; Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989; Alvestad et al., 2003; Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
UOM: 1 * 50 µl


Proveedor: MERCK PRODUCTION CHEMICALS
Descripción: Alcohol polivinílico, M.W. 115,000 ≥88%, EMPROVE® EXPERT Ph. Eur., USP, JPE suitable for use as excipient, hydrolysed, SAFC®

FDS

Numero del catalogo: (STMC100-1333)
Proveedor: STEMCELL Technologies
Descripción: Fetuin B is thought to have functions in female fertility, metabolism, and liver disease. A protease inhibitor belonging to the fetuin family of proteins, within the cystatin superfamily, fetuin b’s structure includes two cystatin domains (CY1 and CY2) connected by a linker, with a CPDCP-trunk and a C-terminal region (CTR) (Cuppari <i>et al.</i>). This plasma protein originates in the liver (Denecke <i>et al.</i>) and acts to inhibit the activity of ovastacin, a metalloprotease that causes the zona pellucida to harden, leading to female infertility (Karmilin <i>et al.</i>). Fetuin B has also been reported to increase apoptosis, and inhibit migration and invasion of prostate cancer cells, in in vitro and <i>in vivo</i> settings (Zhan <i>et al.</i>). Elevated serum fetuin B has been linked to non-alcoholic fatty liver disease (NAFLD) (Zhu <i>et al.</i>). This protein contains a His-residue tag at the carboxyl end of the polypeptide chain. For consistency and reproducibility across your applications, apolipoprotein H from STEMCELL comes lyophilised with ≥92% purity, and is verified by LAL analysis to ensure endotoxin levels are ≤1,0 EU/μg protein.
UOM: 1 * 100 µG

New Product

Market Source Item This is a MarketSource item. Additional charges may apply

Proveedor: MERCK PRODUCTION CHEMICALS
Descripción: Alcohol bencílico 98.0-100.5% (por GC), EMPROVE® ESSENTIAL NF, JP, Ph. Eur., BP suitable for use as excipient, SAFC®
Numero del catalogo: (STMC100-0930)
Proveedor: STEMCELL Technologies
Descripción: Interleukin 34 (IL-34) is well known for its ability to induce the formation of colony-forming unit macrophages in human bone marrow cell cultures (Foucher <i>et al.</i>; Wei <i>et al.</i>). This dimeric glycoprotein is a member of the short-chain helical hematopoietic cytokine family (Baghdadi <i>et al.</i>; Foucher <i>et al.</i>), and exists in two isoforms that differ by a single glutamine (Chen <i>et al.</i>; Foucher et al; Wei <i>et al.</i>). IL-34 interacts with M-CSF to trigger tyrosine phosphorylation of the receptor and ERK1/2 pathways. (Wang <i>et al.</i>; Wei <i>et al.</i>). It is expressed in many tissues (heart, brain, lung, liver, kidney, thymus, testes, ovary, small intestine, prostate, and colon), with the highest expression in the spleen. In combination with RANKL, IL-34 induces osteoclast differentiation (Chen <i>et al.</i>; Foucher <i>et al.</i>). IL-34 expression is decreased in Alzheimer’s disease and atopic dermatitis, while high levels of IL-34 are found in many types of cancer correlated with poor prognosis, chronic heart failure or coronary artery disease, inflammatory bowel disease, influenza A infection, during acute liver transplant rejection or in non-alcoholic fatty liver disease, and with rheumatoid arthritis (Baghdadi <i>et al.</i>). It is therefore a possible pharmacological target for treating bone or inflammatory diseases (Chen <i>et al.</i>). This protein contains a His-residue tag at the carboxyl end of the polypeptide chain, and the protein was purified as a homodimer consisting of 39 kDa monomers (Lin <i>et al.</i>).
UOM: 1 * 100 µG

Market Source Item This is a MarketSource item. Additional charges may apply

Proveedor: MERCK PRODUCTION CHEMICALS
Descripción: For full details of specification and hazards please see www.vwr.com

Environmentally Preferable

Numero del catalogo: (03770-5L)
Proveedor: Honeywell Chemicals
Descripción: Etilenglicol, grado técnico suitable as anti-freezing agent (with corrosion-inhibitor), blue
UOM: 1 * 5 L

FDS


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El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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