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Product Image-STMC100-1386

EBV (EBNA-3A) Peptide Pool

Descripción: Stimulating T cells with EBV (EBNA-3A) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. EBV (EBNA-3A) Peptide pool is a lyophilised mixture of 234 peptides from Epstein-Barr nuclear antigen 3 (EBNA-3A) of Epstein-Barr virus (EBV; strain B95-8) and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 944 on EBNA-3A. EBNA-3A contributes to B cell growth transformation (Hertle <i>et al.</i>; Tomkinson <i>et al.</i>) and has been found to interact with host cell proteins, where it activates (Young <i>et al.</i>) or represses (Cludts and Farrell; Hickabottom <i>et al.</i>) transcription of specific cellular genes. Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
Numero del catalogo: STMC100-1386
UOM: 1 * 1 UP
Proveedor: STEMCELL Technologies

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Product Image-STMC100-1405

CMV (UL44) Peptide Pool

Descripción: Stimulating T cells with CMV (UL44) peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. CMV (UL44) peptide pool is a lyophilised mixture of 106 peptides from DNA polymerase processivity factor UL44 of human cytomegalovirus (CMV; strain AD169), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 433 on UL44. UL44 contains a nuclear localization signal (Alvisi <i>et al.</i>) and may bind DNA directly, or form a C clamp partially surrounding it, similar to proliferation cell nuclear antigen (PCNA) (Appleton <i>et al.</i>). UL44 has also been found to interact with viral (Kim and Ahn) and host (Strang <i>et al.</i>) proteins that contribute to viral DNA replication and efficient viral growth. Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
Numero del catalogo: STMC100-1405
UOM: 1 * 1 UP
Proveedor: STEMCELL Technologies

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Image Unavailable-TCIAH1030-1G

L-Homoserina ≥98.0% (by titrimetric analysis)

Descripción: L-Homoserina ≥98.0% (by titrimetric analysis)
Numero del catalogo: TCIAH1030-1G
UOM: 1 * 1 g
Proveedor: TCI
Product Image-F-124S

Phire® Green Hot Start II DNA Polymerase

Descripción: Phire® Hot Start II DNA Polymerase is faster, extremely robust, and capable of amplifying long DNA fragments with high yields. Phire® Hot Start II DNA Polymerase incorporates a dsDNA-binding domain which allows short extension times (10 to 15 s/kb), improves yields, and increases fidelity 2-fold compared to <i>Taq</i> DNA polymerase. In addition, the Hot Start technology allows complete reactivation of the enzyme in “zero-time” at standard cycling temperatures. This combination of features makes the polymerase an ideal solution for routine and high throughput PCR applications. Phire® Hot Start II DNA Polymerase delivers superior performance in conventional thermal cyclers as well as in fast instruments, such as the Piko® Thermal Cycler.
Numero del catalogo: F-124S
UOM: 1 * 1 KIT
Proveedor: FINNZYMES REAGENTS
Product Image-F-122S

Phire® Hot Start II DNA polymerase

Descripción: Phire® Hot Start II DNA Polymerase is faster, extremely robust, and capable of amplifying long DNA fragments with high yields. Phire® Hot Start II DNA Polymerase incorporates a dsDNA-binding domain which allows short extension times (10 to 15 s/kb), improves yields, and increases fidelity 2-fold compared to <i>Taq</i> DNA polymerase. In addition, the Hot Start technology allows complete reactivation of the enzyme in “zero-time” at standard cycling temperatures. This combination of features makes the polymerase an ideal solution for routine and high throughput PCR applications. Phire® Hot Start II DNA Polymerase delivers superior performance in conventional thermal cyclers as well as in fast instruments, such as the Piko® Thermal Cycler.
Numero del catalogo: F-122S
UOM: 1 * 1 KIT
Proveedor: FINNZYMES REAGENTS
Product Image-PRSI32-215

Anti-SNCA Mouse Monoclonal Antibody

Descripción: Alpha-synuclein (SNCA), with 140-amino acid protein (about 15 kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy.
Numero del catalogo: PRSI32-215
UOM: 1 * 100 µl
Proveedor: ProSci Inc.
Image Unavailable-ICNA0210142310

2-Imino-1-metilimidazolidin-4-ona, anhidro 98.5-102%, white powder

Descripción: Creatinine, the end product of creatine catabolism is a normal constituent of urine; daily output about 25 mg/kg body weight. The increased amounts in the urine are typically associated with substantially impaired renal function. Also found together with creatine in muscle tissues and blood. It reacts with picric acid under alkaline conditions to form a Janovski complex. The rate of formation of the colored complex, measured at 480-520 nm is proportional to the creatinine concentration.
Creatinine is a useful marker for normalizing levels of other molecules found in urine and the altered creatinine levels may be associated with conditions that result in decreased renal blood flow, such as diabetes and cardiovascular disease.
Numero del catalogo: ICNA0210142310
UOM: 1 * 10 g
Proveedor: MP Biomedicals
Product Image-STMC100-1420

SARS-CoV-2 (Spike Protein) Omicron/B.1.1.529 Peptide Pool

Descripción: Stimulating T cells with SARS-CoV-2 (Spike Protein) Omicron/B.1.1.529 Peptide Pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. This pool is provided as two lyophilised mixtures (subpools) from the spike glycoprotein of SARS-CoV-2 Omicron variant (B.1.1.529), which contain 158 and 157 peptides, respectively, for a total of 315 peptides. They consist of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 1270 on the spike protein. Through interactions with the angiotensin-converting enzyme 2 (ACE2) receptor, the spike protein enables the virus to attach to the cell membrane, and plays a critical role in viral entry (Hoffmann <i>et al.</i>; Walls <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
Numero del catalogo: STMC100-1420
UOM: 1 * 1 UP
Proveedor: STEMCELL Technologies

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Product Image-STMC100-1421

SARS-CoV-2 (Spike Protein) Omicron BA.4/BA.5 Peptide Pool

Descripción: Stimulating T cells with SARS-CoV-2 (Spike Protein) Omicron BA.4/BA.5 Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. This pool is provided as two lyophilised mixtures (subpools) from the spike glycoprotein of SARS-CoV-2 Omicron BA.4/BA.5 subvariant. The subpools contain 158 and 157 peptides, respectively, for a total of 315 peptides, and they consist of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 1270 on the spike protein. Through interactions with the angiotensin-converting enzyme 2 (ACE2) receptor, the spike protein enables the virus to attach to the cell membrane, and plays a critical role in viral entry (Hoffmann <i>et al.</i>; Walls <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
Numero del catalogo: STMC100-1421
UOM: 1 * 1 UP
Proveedor: STEMCELL Technologies

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Product Image-STMC100-1395

HPV16 (E6) Peptide Pool

Descripción: Stimulating T cells with HPV16 (E6) Peptide Pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. HPV16 (E6) Peptide Pool is a lyophilised mixture of 37 peptides from the E6 protein of human papillomavirus type 16 (HPV16). The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 158 on protein E6. E6 binds to the tumor suppressor protein p53 and stimulates its degradation (Scheffner <i>et al.</i>; Werness <i>et al.</i> ), which is thought to cause an increase in spontaneous mutagenesis in host cells (Havre <i>et al.</i>). E6 together with E7 demonstrated the ability to immortalize human keratinocytes in vitro, which likely has significance for HPVs oncogenic potential (Hawley-Nelson <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
Numero del catalogo: STMC100-1395
UOM: 1 * 1 UP
Proveedor: STEMCELL Technologies

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Product Image-STMC100-1402

HHV6 (U90) Peptide Pool

Descripción: Stimulating T cells with HHV6 (U90) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. HHV6 (U90) Peptide pool is a lyophilised mixture of 267 peptides from protein U90 of human herpesvirus 6B (HHV-6B; strain Z29) and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 1078 on U90. U89 - U90 RNA expression occurs under immediate-early conditions of infection (Mirandola <i>et al.</i>), and the associated protein exhibits peri-nuclear and cytoplasmic localization (Nikolaou <i>et al.</i>). Also known as immediate-early protein IE1, latency-associated transcripts of HHV6 may function as a source of IE1 during viral reactivation (Kondo <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
Numero del catalogo: STMC100-1402
UOM: 1 * 1 UP
Proveedor: STEMCELL Technologies

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Product Image-STMC100-1412

CMV (IE2) Peptide Pool

Descripción: Stimulating T cells with CMV (IE-2) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. CMV (IE-2) Peptide pool is a lyophilised mixture of 143 peptides from immediate early protein 2 (IE2) of human cytomegalovirus (CMV; strain AD169), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 580 on IE2. IE2 is critical for viral infection and for the expression of CMV early genes (Marchini <i>et al.</i>). It also controls transcription initiation for a subset of early-late and late viral promoters via RNA polymerase II (Li <i>et al.</i>). IE2, along with IE1, may contribute to the survival of CMV-infected cells by blocking tumor necrosis factor alpha (TNF-α)-induced apoptosis (Zhu <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
Numero del catalogo: STMC100-1412
UOM: 1 * 1 UP
Proveedor: STEMCELL Technologies

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Product Image-662-2017

pH tester, Eutech pHTestr 30

Descripción: This water- and dust-proof tester is ideal for quick and accurate pH checks in pools and spas, aquariums and hydroponics operations, cooling towers, food processing water and process/wastewater. The double junction electrode makes the tester ideal for dirty water and solutions with heavy metals or contaminants, while increased reference gel volume offers significantly longer electrode life. Also suitable for educational purposes in schools.
Numero del catalogo: 662-2017
UOM: 1 * 1 UN
Proveedor: EUTECH
Image Unavailable-ICNA0219482580

Glicina ≥99% para biología molecular

Descripción: Storage: Store at Room Temperature (15-30 °C)
Glycine is a non-essential amino acid. It is only amino acid with no asymmetric carbon and thus is not chiral. It is the major inhibitory neurotransmitter. It is involved in the biosynthesis of the porphyrin rings of hemes and chlorophylls.
Glycine is commonly used in buffer solutions, in electrophoresis and preparative chromatography. A study of the folding of monoclonal antibodies in the presence of glycine and their subsequent purification has been published. The use of glycine in the purification of lipopolysaccharides, lipooligosaccharides, and lipid A has been reported. It is an amino acid for use in cell culture media development applications and existing media formulations. Glycine is commonly used as a component in Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis, a component of Towbin's transfer buffer for Western blots, a buffer substance in cryoenzymology, in osmotic pressure maintenance in isoelectric focusing of erythrocytes, salting-in effect in protein chemistry, and as a buffer component in the coupled phosphatase-kinase reaction for end labelling of restriction fragments. The growth requirements of various microorganisms is reported in the Handbook of Microbiology.
Glycine is a non-chiral amino acid that can be synthesized in the body from the amino acid serine by Serine Hydroxymethyltransferase. Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Numero del catalogo: ICNA0219482580
UOM: 1 * 100 g
Proveedor: MP Biomedicals
Product Image-662-0415

pH/mV/°C meter, handheld, 826

Descripción: Handy and easy-to-use pH meter with rugged plastic housing for daily routine work in the laboratory.
Numero del catalogo: 662-0415
UOM: 1 * 1 UN
Proveedor: METROHM
Image Unavailable-ICNA0215245680

PIPES sal sódica

Descripción: PIPES free acid is not very water soluble (approximately 1 g/L at 100 °C) but will solubilise in 0,5 M NaOH.
Numero del catalogo: ICNA0215245680
UOM: 1 * 100 g
Proveedor: MP Biomedicals
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