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Descripción: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Numero del catalogo: BOSSBS-3132R-A680
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Non-ionic detergent used for membrane protein solubisation. An advantage of OG is its low molecular weight which allows easy removal by dialysis.
Numero del catalogo: APOSBIMB1075-1G
UOM: 1 * 1 g
Proveedor: Apollo Scientific


Descripción: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Numero del catalogo: BOSSBS-3132R-CY5
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Numero del catalogo: BOSSBS-5223R-CY5.5
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Numero del catalogo: BOSSBS-5223R-CY7
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Numero del catalogo: BOSSBS-2765R-A350
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Numero del catalogo: BOSSBS-2765R-CY3
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
Numero del catalogo: BOSSBS-3398R-CY3
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Numero del catalogo: BOSSBS-5537R-CY5
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Numero del catalogo: BOSSBS-2739R-CY5.5
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: X-Gal es un sustrato cromogénico para la ß-Galactosidasa que forma un precipitado de color azul intenso. Al utilizarlo con IPTG en un análisis colorimétrico, el X-Gal permite diferenciar los recombinantes de los no recombinantes en los ensayos de clonación con vectores que contengan el gen<italic> lac Z</italic>. También se usa en microbiología para detectar microorganismos con actividad ß-Galactosidasa.
Numero del catalogo: 437132J
UOM: 1 * 1 g
Proveedor: VWR Chemicals

FDS Certificados


Descripción: X-Gal (5-Bromo-4-cloro-3-indolil-ß-D-galactopiranósido) ≥98.0% (by HPLC, total nitrogen) for biochemical research
Numero del catalogo: TCIAB3201-1G
UOM: 1 * 1 g
Proveedor: TCI


Descripción: X-Gal, a chromogenic substrate of beta-Galactosidase. Used in conjunction with IPTG for detection of beta-Galactosidase activity in bacterial colonies in a colorimetric assay.
Numero del catalogo: APOSBIMB1001-1G
UOM: 1 * 1 g
Proveedor: Apollo Scientific


Descripción: X-Gal (5-Bromo-4-cloro-3-indolil-ß-D-galactopiranósido) 99+% para biología molecular DNase-, RNase-, protease-free
Numero del catalogo: ACRO327241000
UOM: 1 * 100 mg
Proveedor: Thermo Fisher Scientific

FDS


Descripción: Un análogo químico de la galactosa que no puede ser hidrolizado por el enzima ß-Galactosidasa. El IPTG es un inductor del operón lac de <i>E.coli</i> que actúa fijando e inhibiendo el represor lac. Los genes controlados por la secuencia promotor/operador lac se expresan en niveles elevados en presencia de IPTG. Esencialmente libres de dioxano.
Numero del catalogo: 43714BD
UOM: 1 * 1 kg
Proveedor: VWR Chemicals

FDS Certificados


Descripción: D-Glucono-1,5-lactona ≥98.0% (by titrimetric analysis)
Numero del catalogo: TCIAG0039-25G
UOM: 1 * 25 g
Proveedor: TCI


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