Esta buscando: CL-82198+(MMP-13+inhibitor)


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Proveedor: ENZO LIFE SCIENCES
Descripción: A novel and selective inhibitor of MMP-13 (89% at 33 µM). Acts via binding to the S1' pocket of MMP-13 without metal chelation.

Proveedor: ENZO LIFE SCIENCES
Descripción: Potent MMP-13 inhibitor.

Numero del catalogo: (ENZOBMLAK4120001)
Proveedor: ENZO LIFE SCIENCES
Descripción: A QuantiZyme™ Assay System. The MMP-13 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-13 (MMP-13, collagenase-3) using a thiopeptide as a chromogenic substrate.
UOM: 1 * 1 KIT


Numero del catalogo: (ENZOBMLAK4130001)
Proveedor: ENZO LIFE SCIENCES
Descripción: A QuantiZyme™ Assay System. The MMP-13 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-13 (MMP-13, collagenase-3) using a quenched fluorogenic peptide: OmniMMP™ fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.
UOM: 1 * 1 KIT


Numero del catalogo: (ENZOBMLP1450001)
Proveedor: ENZO LIFE SCIENCES
Descripción: Quenched fluorogenic substrate for cathepsin D (kcat/Km=1,09×10 M-1s-1) and cathepsin E (kcat/Km=1,56×10 M-1s-1). Mca fluorescence is quenched by the Dnp group until cleavage separates them. Activity of the two enzymes on this substrate can be distinguished by the use of Ascaris pepsin inhibitor, which inhibits cathepsin E, but not cathepsin D. This substrate is also cleaved by MMP-2, MMP-3, MMP-9, but not MMP-1 nor MMP-13. This substrate is useful for inhibitor screening and kinetic analysis. Ex.: 320-340 nm, Em.: 393-420 nm. Mca-Pro-Leu-OH (BML-P127) can be used to calibrate for Mca fluorescence.
UOM: 1 * 1 mg


Numero del catalogo: (ENZOBMLP2350001)
Proveedor: ENZO LIFE SCIENCES
Descripción: Fluorogenic substrate for ADAM8 (kcat/Km = 1,0×105 M-1s-1), ADAM10 (6,2×103), ADAM12 (2,8×105), TACE (TNF-α converting enzyme, ADAM17) (4,3×105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485 nm, Em.: 530 nm. This substrate is useful for inhibitor screening and kinetic analysis.
UOM: 1 * 1 mg


Numero del catalogo: (ENZOBMLP1320500)
Proveedor: ENZO LIFE SCIENCES
Descripción: Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OMNIMMP® Fluorogenic Control peptide (BML-P127).
UOM: 1 * 0,5 mg


Numero del catalogo: (444252-1)
Proveedor: Merck Millipore (Calbiochem‎)
Descripción: A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 (IC₅₀=900 pM) and MMP-13 (IC₅₀=900 pM).
UOM: 1 * 1 mg


Numero del catalogo: (PRSI91-415)
Proveedor: ProSci Inc.
Descripción: Tissue Inhibitor of Metalloproteinases 2 (TIMP-2) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
UOM: 1 * 50 µG


Numero del catalogo: (ENZOBMLEI3990010)
Proveedor: ENZO LIFE SCIENCES
Descripción: Novel inhibitor of ubiquitin C-terminal hydrolase L3 (IC50 = 0.6µM). Displays 125-fold greater selectivity over UCH-L1 (IC50 = 75µM).
UOM: 1 * 10 mg


Numero del catalogo: (PRSI91-412)
Proveedor: ProSci Inc.
Descripción: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
UOM: 1 * 50 µG


Proveedor: ENZO LIFE SCIENCES
Descripción: Cytochrome P450 inhibitor

Numero del catalogo: (PRSI92-603)
Proveedor: ProSci Inc.
Descripción: Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16. TIMP-1 does not act on MMP-14.
UOM: 1 * 50 µG


Numero del catalogo: (ENZOALX430155M002)
Proveedor: ENZO LIFE SCIENCES
Descripción: Selective and cell permeable inhibitor of the interaction between the human eukaryotic translation initiation factors 4E (eIF4E) and 4G (eIF4G).
UOM: 1 * 2 mg


Numero del catalogo: (ENZOENZCHM1330001)
Proveedor: ENZO LIFE SCIENCES
Descripción: Cell-permeable, potent, selective, and reversible MMP-9 inhibitor.
UOM: 1 * 1 mg


Numero del catalogo: (ENZOALX260165M005)
Proveedor: ENZO LIFE SCIENCES
Descripción: Inhibitor of matrix metalloproteinase 3 (MMP-3) (IC50=5µM).
UOM: 1 * 5 mg


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El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
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Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
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