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Esta buscando: CL-82198+(MMP-13+inhibitor)


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Image Unavailable-BOSSBS-5859R-HRP

Anti-ADAMTS8 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numero del catalogo: (BOSSBS-5859R-HRP)
Proveedor: Bioss
Descripción: ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0417R-HRP

Anti-TIMP3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numero del catalogo: (BOSSBS-0417R-HRP)
Proveedor: Bioss
Descripción: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0417R-A555

Anti-TIMP3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numero del catalogo: (BOSSBS-0417R-A555)
Proveedor: Bioss
Descripción: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
UOM: 1 * 100 µl
Image Unavailable-PRSI92-458

Human recombinant TIMP-4 (from cells)

Numero del catalogo: (PRSI92-458)
Proveedor: ProSci Inc.
Descripción: Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
UOM: 1 * 50 µG
Image Unavailable-91301-500ML

Diclorometano ≥99.5% (por GC) inhibitor-free, Selectophore™ ionophore, Supelco®

Numero del catalogo: (91301-500ML)
Proveedor: Merck
Descripción: Diclorometano ≥99.5% (por GC) inhibitor-free, Selectophore™ ionophore, Supelco®
UOM: 1 * 500 mL
Image Unavailable-ENZOENZCHM1310001

Cdk/Crk inhibitor ≥98% (by HPLC)

Numero del catalogo: (ENZOENZCHM1310001)
Proveedor: ENZO LIFE SCIENCES
Descripción: Potent, selective, and ATP-competitive inhibitor of Cdks. Antiproliferative.
UOM: 1 * 1 mg
Image Unavailable-PRSI33-214

Anti-TIMP3 Rabbit Polyclonal Antibody

Numero del catalogo: (PRSI33-214)
Proveedor: ProSci Inc.
Descripción: TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP’s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.
UOM: 1 * 100 µG

New Product


Product Image-PRSI96-720

Human recombinant TIMP1 (from HEK293 cells)

Numero del catalogo: (PRSI96-720)
Proveedor: ProSci Inc.
Descripción: TIMP metallopeptidase inhibitor 1 is also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein a member of the TIMP family.There are four members of the family, TIMP1,TIMP2,TIMP3 and TIMP4. TIMP1 is a glycoprotein with a molecular mass of 28 kDa produced by a wide range of cell types. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
UOM: 1 * 50 µG
Image Unavailable-ENZOBMLNS1110050

Bupropion hydrochloride ≥98% (by TLC)

Proveedor: ENZO LIFE SCIENCES
Descripción: Inhibitor of dopamine and norepinephrine transporters

Product Image-PRSI55-700

Anti-TIMP1 Rabbit Polyclonal Antibody

Numero del catalogo: (PRSI55-700)
Proveedor: ProSci Inc.
Descripción: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
UOM: 1 * 400 µl

New Product


Image Unavailable-ENZOALX385013M010

3,5,7,4'-Tetrahydroxy-3',5'-dimethoxyflavylium chloride ≥97% (by HPLC)

Numero del catalogo: (ENZOALX385013M010)
Proveedor: ENZO LIFE SCIENCES
Descripción: Cell cycle inhibitor
UOM: 1 * 10 mg
Image Unavailable-ENZOBMLRA1130025

SC-51089 ≥98%

Numero del catalogo: (ENZOBMLRA1130025)
Proveedor: ENZO LIFE SCIENCES
Descripción: Prostanoid receptor inhibitor
UOM: 1 * 25 mg
Image Unavailable-ENZOBMLGR3500025

ITSA-1 ≥98% (by TLC)

Numero del catalogo: (ENZOBMLGR3500025)
Proveedor: ENZO LIFE SCIENCES
Descripción: HDAC inhibitor
UOM: 1 * 25 mg
Image Unavailable-ENZOBMLEI1280001

Ethacrynic acid ≥99%

Numero del catalogo: (ENZOBMLEI1280001)
Proveedor: ENZO LIFE SCIENCES
Descripción: GST inhibitor
UOM: 1 * 1 g
Image Unavailable-ENZOALX420036M025

DICA ≥98% (by TLC)

Numero del catalogo: (ENZOALX420036M025)
Proveedor: ENZO LIFE SCIENCES
Descripción: Inhibitor of caspase-3 and caspase-7 binding to an allosteric site and not to the active site.
UOM: 1 * 25 mg
Image Unavailable-ENZOBMLPD1410050

Irsogladine maleate ≥98%

Numero del catalogo: (ENZOBMLPD1410050)
Proveedor: ENZO LIFE SCIENCES
Descripción: PDE inhibitor
UOM: 1 * 50 mg
Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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