Esta buscando: Chloramphenicol+sodium+succinate

Numero del catalogo: (PRSI6847)

Proveedor: ProSci Inc.

Descripción: SDHD Antibody: The mitochondrial succinate dehydrogenase complex subunit D (SDHD) is one of four proteins that make up the tricarboxylic cycle enzyme succinate dehydrogenase (SCH). Studies have shown that mutations in SDHD often leads to hereditary paragangliomas, usually benign tumors of the autonomic nervous system, suggesting that SDHD also plays a role as a tumor-suppressor gene. In one family with a nonsense mutation (R22X) in the SDHD gene, a loss of heterozygosity was found in the paragangliomas, and within these tumors the enzymatic activity of Complex II in the mitochondrial respiratory chain was completely abolished. Furthermore, high levels of angiogenic factors EPAS1 and VEGF was observed, which may stimulate tumor growth.

UOM: 1 * 100 µG

Promoción

Numero del catalogo: (BSBTPB9433)

Proveedor: Boster Bio

Descripción: Rabbit IgG polyclonal antibody for Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human;Mouse;Rat.

UOM: 1 * 100 µG

Promoción

Numero del catalogo: (BSBTPA1718)

Proveedor: Boster Bio

Descripción: Rabbit IgG polyclonal antibody for Succinate dehydrogenase[ubiquinone] iron-sulfur subunit, mitochondrial (SDHB) detection. Tested with WB, IHC-P in Human; Mouse; Rat.

UOM: 1 * 0,1 mg

Promoción

Numero del catalogo: (USBI123176)

Proveedor: US Biological

Descripción: Anti-AKR7A2 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

Promoción

Proveedor: MP Biomedicals

Descripción: Thenoyltrifluoroacetone is used as a reagent for the extraction and spectrophotometric determination of metals, actinides and lanthanides. A metal ion chelator that acts as an inhibitor of electron transport complex II in the mitochondrial respiratory chain. Also acts as an inhibitor of succinate and maleate dehydrogenases.

Proveedor: MP Biomedicals

Descripción: Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and requires five equivalents of sulfuric acid per mole of gentamicin base. Mode of action: Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site.The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface.Antimicrobial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria. Gentamicin sulfate is a broad spectrum antibiotic. It inhibits the growth of a wide variety of Gram-positive and Gram-negative microorganisms, including strains resistant to tetracycline, chloramphenicol, kanamycin, and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus, and Streptococcus. Gentamicin sulfate inhibits bacterial protein biosynthesis by binding to the 30S subunit of the ribosome.

Numero del catalogo: (PRSI56-248)

Proveedor: ProSci Inc.

Descripción: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane. Mutations in SDHD have been linked to hereditary paraganglioma.

UOM: 1 * 400 µl

New Product Promoción

Numero del catalogo: (PRSI26-268)

Proveedor: ProSci Inc.

Descripción: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UOM: 1 * 50 µG

Promoción

Numero del catalogo: (PRSI6507)

Proveedor: ProSci Inc.

Descripción: SDHAF2 Antibody: SDHAF2 (Succinate dehydrogenase complex assembly factor 2) encodes a mitochondrial protein needed for FAD cofactor attach to the SDH enzyme which plays a critical role in mitochondria. SDHAF2 is a tumor suppressor, but recent evidence suggests that somatic mutations of the SDHAF2 are unlikely to contribute to parathyroid tumor development in sporadic primary hyperparathyroidism.

UOM: 1 * 100 µG

Promoción

Numero del catalogo: (PRSI26-612)

Proveedor: ProSci Inc.

Descripción: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

UOM: 1 * 50 µG

Promoción

Numero del catalogo: (PRSI4807)

Proveedor: ProSci Inc.

Descripción: Aldh5A1 Antibody: Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.

UOM: 1 * 100 µG

Promoción

Numero del catalogo: (LIOF15365S)

Proveedor: LIOFILCHEM

Descripción: <p>Contact plates are used for monitoring surfaces, air, and personnel inside cleanrooms and sterile areas. The peelable blister pack ensures the highest quality and protection standards for the plates and reduces waste.</p>

UOM: 1 * 20 UN

New Product Promoción

Numero del catalogo: (8.41813.0010)

Proveedor: Merck

Descripción: Sodium-1-hexadecanesulphonate para síntesis, Sigma-Aldrich®

UOM: 1 * 10 g

FDS Promoción

Proveedor: Merck

Descripción: Sodium carbonate : Sodium hydroxide concentrada (150 mM : 15 mM) in water IC eluent concentrate (20x) for Metrosep A Supp 16, Supelco®

Numero del catalogo: (8.22145.0250)

Proveedor: Merck

Descripción: Sodium sulphanilate dihydrate sodium salt para síntesis, Sigma-Aldrich®

UOM: 1 * 250 g

FDS Promoción

Proveedor: Merck

Descripción: The “bicarbonate concentrate” is 1-molar solution of sodium bicarbonate (the saturation temperature of the 1-molar solution is 15°C). It is highly advantageous as it is temperature dependent and its subsequent dilution with water can be appropriately controlled

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