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Descripción: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
Numero del catalogo: BOSSBS-11788R-CY7
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Numero del catalogo: BOSSBS-0988R-FITC
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
Numero del catalogo: BOSSBS-11788R-A555
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.
Numero del catalogo: BOSSBS-7157R-CY3
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.
Numero del catalogo: BOSSBS-7157R-CY5.5
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.
Numero del catalogo: BOSSBS-7157R-A647
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Agitador magnético resistente con carcasa de acero inoxidable herméticamente sellada, adecuado para medios muy viscosos. Tiempos de intervalo ajustables para reinicio automático después de un máximo de 240 segundos. Temperaturas de funcionamiento hasta 50 °C. Ajuste de la potencia en cuatro etapas.
Numero del catalogo: 442-0803
UOM: 1 * 1 UN
Proveedor: 2MAG


Descripción: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Numero del catalogo: BOSSBS-6053R-A750
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Numero del catalogo: BOSSBS-6053R-A647
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Numero del catalogo: BOSSBS-6053R-A555
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions.
Numero del catalogo: BOSSBS-15417R-CY3
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Anti-GFP VHH Single Domain Llama Monoclonal Antibody [clone: NB102] (Magnetic beads)
Numero del catalogo: ABCAAB193983-500
UOM: 1 * 500 µl
Proveedor: Abcam


Descripción: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Numero del catalogo: BOSSBS-6053R-FITC
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Numero del catalogo: BOSSBS-6053R-HRP
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Numero del catalogo: BOSSBS-6053R-A680
UOM: 1 * 100 µl
Proveedor: Bioss


Descripción: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
Numero del catalogo: BOSSBS-12565R-A647
UOM: 1 * 100 µl
Proveedor: Bioss


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