Esta buscando: Dispensadores de agua

Numero del catalogo: (BOSSBS-10123R-HRP)

Proveedor: Bioss

Descripción: IKK Alpha/IKK beta is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-1910R-A750)

Proveedor: Bioss

Descripción: Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localises transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-4908R)

Proveedor: Bioss

Descripción: Anti-TGF beta 1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-4538R)

Proveedor: Bioss

Descripción: Anti-TGF Beta 1+2+3 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Promoción

Proveedor: Avantor

Descripción: Reduce risk in your bioprocessing applications with Avantor J.T.Baker brand cGMP manufactured IPTG.

FDS Certificados

Proveedor: Thermo Fisher Scientific

Descripción: Methyl-β-D-thiogalactoside 98%

Numero del catalogo: (BWRLAP0064)

Proveedor: Bioworld Technology

Descripción: Recombinant full length Human Tubulin beta.

UOM: 1 * 100 µG

Promoción

Proveedor: Apollo Scientific

Descripción: Methyl-1,2,3,4-tetra-O-acetyl-β-D-glucuronate

Numero del catalogo: (USBI0014-02P)

Proveedor: US Biological

Descripción: Anti-14-3-3 beta Rabbit Polyclonal Antibody

UOM: 1 * 50 µG

Promoción

Numero del catalogo: (USBI0014-02M)

Proveedor: US Biological

Descripción: Anti-14-3-3 beta Rabbit Polyclonal Antibody

UOM: 1 * 50 µG

Promoción

Proveedor: Thermo Fisher Scientific

Descripción: CAS No.: 6974-32-9

FDS

Numero del catalogo: (BOSSBS-0486R-A750)

Proveedor: Bioss

Descripción: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognise the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognises one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognises the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognises the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognise the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-10429R-A680)

Proveedor: Bioss

Descripción: The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-10429R-A750)

Proveedor: Bioss

Descripción: The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BWRLMB0001)

Proveedor: Bioworld Technology

Descripción: Recombinant full length Human Arrestin-beta-1.

UOM: 1 * 100 µG

Promoción

Numero del catalogo: (BWRLBS6950)

Proveedor: Bioworld Technology

Descripción: Recombinant full length Human Tubulin beta.

UOM: 1 * 100 µG

Promoción