Esta buscando: Ginsenoside+Rb1

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Anti-RB1 Rabbit Polyclonal Antibody

Numero del catalogo: (USBI040868)

Proveedor: US Biological

Descripción: Anti-RB1 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Promoción

N/A Each

Anti-RB1 Rabbit Polyclonal Antibody

Numero del catalogo: (USBIR1660-05G1)

Proveedor: US Biological

Descripción: Anti-RB1 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Promoción

N/A Each

Anti-RB1 Rabbit Polyclonal Antibody

Numero del catalogo: (USBIR1660-05G5)

Proveedor: US Biological

Descripción: Anti-RB1 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

Promoción

N/A Each

Anti-RB1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Numero del catalogo: (USBIR1660-05K-PE)

Proveedor: US Biological

Descripción: Anti-RB1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))

UOM: 1 * 200 µl

Promoción

N/A Each

Anti-RB1 Rabbit Polyclonal Antibody (Cy5®)

Numero del catalogo: (BOSSBS-2777R-CY5)

Proveedor: Bioss

Descripción: Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, SUV42H1 and SUV42H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-2' trimethylation. Inhibits the intrinsic kinase activity of TAF1. Mediates transcriptional repression by SMARCA4/BRG1 by recruiting a histone deacetylase (HDAC) complex to the c-FOS promoter. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex (By similarity). In case of viral infections, interactions with SV4 large T antigen, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity.

UOM: 1 * 100 µl

Promoción