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Image Unavailable-BOSSBS-6010R

Anti-GTPBP4 Rabbit Polyclonal Antibody

Numero del catalogo: (BOSSBS-6010R)
Proveedor: Bioss
Descripción: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [Entrez Gene]
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0829R-CY5.5

Anti-NANOG Rabbit Polyclonal Antibody (Cy5.5®)

Numero del catalogo: (BOSSBS-0829R-CY5.5)
Proveedor: Bioss
Descripción: Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-9377R-HRP

Anti-UBE2V2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numero del catalogo: (BOSSBS-9377R-HRP)
Proveedor: Bioss
Descripción: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13258R

Anti-GABBR2 Rabbit Polyclonal Antibody

Numero del catalogo: (BOSSBS-13258R)
Proveedor: Bioss
Descripción: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1064R-A350

Anti-KLF4 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numero del catalogo: (BOSSBS-1064R-A350)
Proveedor: Bioss
Descripción: Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1064R-A555

Anti-KLF4 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numero del catalogo: (BOSSBS-1064R-A555)
Proveedor: Bioss
Descripción: Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9377R-A647

Anti-UBE2V2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Numero del catalogo: (BOSSBS-9377R-A647)
Proveedor: Bioss
Descripción: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9881R-A750

Anti-GFI1B Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numero del catalogo: (BOSSBS-9881R-A750)
Proveedor: Bioss
Descripción: Essential proto-oncogenic transcriptional regulator necessary for development and differentiation of erythroid and megakaryocytic lineages. Transcriptional repressor or activator depending on both promoter and cell type context; represses promoter activity of SOCS1 and SOCS3 and thus, may regulate cytokine Signalling pathways. Cooperates with GATA1 to repress target gene transcription, such as the apoptosis regulator BCL2L1; GFI1B silencing in leukemic cell lines markedly increase apoptosis rate. Inhibits down-regulation of MYC and MYB as well as the cyclin-dependent kinase inhibitor CDKN1A/P21WAF1 in IL6-treated myelomonocytic cells. Represses expression of GATA3 in T-cell lymphomas and inhibits GATA1-mediated transcription; as GATA1 also mediates erythroid GFI1B transcription, both GATA1 and GFI1B participate in a feedback regulatory pathway controlling the expression of GFI1B gene in erythroid cells. Suppresses GATA1-mediated stimulation of GFI1B promoter through protein interaction. Binds to gamma-satellite DNA and to its own promoter, auto-repressing its own expression. Alters histone methylation by recruiting histone methyltransferase to target genes promoters. Plays a role in heterochromatin formation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9377R-CY5.5

Anti-UBE2V2 Rabbit Polyclonal Antibody (Cy5.5®)

Numero del catalogo: (BOSSBS-9377R-CY5.5)
Proveedor: Bioss
Descripción: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9377R-CY7

Anti-UBE2V2 Rabbit Polyclonal Antibody (Cy7®)

Numero del catalogo: (BOSSBS-9377R-CY7)
Proveedor: Bioss
Descripción: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9377R

Anti-UBE2V2 Rabbit Polyclonal Antibody

Numero del catalogo: (BOSSBS-9377R)
Proveedor: Bioss
Descripción: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
UOM: 1 * 100 µl
Product Image-BURK5344-0400

Sample bags with closure, SteriBag StandUp

Proveedor: BURKLE
Descripción: SteriBag StandUp are sterile sample bags with a stand-up base. The special bottom unfolds as soon as the bag is filled. This makes SteriBag StandUp stable and able to stand on its own without a separate stand or support, leaving both your hands free to take the sample and fill the bag. The wire bracket at the closure keeps the bag open, making it easy and convenient to fill. Can be used for samples available as liquids, powders, solids and pastes; suitable for foods and can be frozen.

Certificados

Image Unavailable-PAWBSTZ-EC-150-10

Avantor SterilEnz®-II/EC: pre-gasketed polypropylene end caps

Proveedor: Avantor Fluid Handling
Descripción: SterilEnz®-II/EC PP end caps are the only end caps that come equipped with a medical grade silicone gasket pre-attached to the fitting face. This feature prevents operators from misaligning or dropping gaskets during assembly. SterilEnz®-II/EC caps work with any standard flange gasket as well. Simply remove the pre-attached gasket (no tools required) and install your own.

Image Unavailable-BOSSBS-1350R-FITC

Anti-EIF4G2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Numero del catalogo: (BOSSBS-1350R-FITC)
Proveedor: Bioss
Descripción: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13258R-A555

Anti-GABBR2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Numero del catalogo: (BOSSBS-13258R-A555)
Proveedor: Bioss
Descripción: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1350R

Anti-DAP5 Rabbit Polyclonal Antibody

Numero del catalogo: (BOSSBS-1350R)
Proveedor: Bioss
Descripción: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
UOM: 1 * 100 µl
Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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