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Malonyl coenzyme A lithium salt ≥90%

Proveedor: Cayman Chemical
Descripción: Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA. Fatty acid synthase catalyzes the NADPH-dependent condensation of malonyl-CoA and acetyl-CoA to produce palmitate. Proliferating human cancer cells upregulate this fatty acid synthesis pathway as a strategy for survival. High levels of malonyl-CoA, achieved through fatty acid synthase inhibition, proposed to contribute to cancer cell apoptosis.

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Supelco® Organic Reference Standard, Malonyl-L-Carnitine Lithium Salt

Proveedor: Merck
Descripción: Organic Standard, Malonyl-ʟ-carnitine lithium salt

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Cerulenin ≥98%, crystalline solid

Proveedor: Cayman Chemical
Descripción: A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.

Image Unavailable-BOSSBS-12952R-A680

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numero del catalogo: (BOSSBS-12952R-A680)
Proveedor: Bioss
Descripción: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
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Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Numero del catalogo: (BOSSBS-12954R-A680)
Proveedor: Bioss
Descripción: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12954R-A750

Anti-Acetyl Coenzyme A Carboxylase alpha Ser80 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Numero del catalogo: (BOSSBS-12954R-A750)
Proveedor: Bioss
Descripción: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12952R-A750

Anti-Acetyl Coenzyme A Carboxylase beta Ser220 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numero del catalogo: (BOSSBS-12952R-A750)
Proveedor: Bioss
Descripción: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyses the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-APOSBIC7401-500MG

Coenzyme A trilithium salt

Proveedor: Apollo Scientific
Descripción: Coenzyme A trilithium salt

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4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Proveedor: Cayman Chemical
Descripción: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

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Coenzyme A sodium salt hydrate ≥95%

Proveedor: Cayman Chemical
Descripción: Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway is identified as a target for the development of antibacterial compounds.

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Acetyl-Coenzyme A Trilithium Salt

Proveedor: Apollo Scientific
Descripción: Acetyl-Coenzyme A Trilithium Salt

Certificados

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Riboflavin 5'-monophosphate sodium salt hydrate

Proveedor: Cayman Chemical
Descripción: Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalysing oxidation and reduction reactions in a variety of biosynthetic pathways.

Certificados

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Calcium pantothenate ≥98% (by HPLC)

Numero del catalogo: (ENZOALX460003G010)
Proveedor: ENZO LIFE SCIENCES
Descripción: Precursor for coenzyme A biosynthesis.
UOM: 1 * 10 g

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Supelco® Organic Reference Standard, D-2-Phosphoglyceric Acid Lithium Salt

Proveedor: Merck
Descripción: Organic Standard, ᴅ-2-Phosphoglyceric acid lithium salt

Image Unavailable-55385-10MG

Supelco® Organic Reference Standard, 3-Phosphoshikimic acid lithium salt

Numero del catalogo: (55385-10MG)
Proveedor: Merck
Descripción: Organic Standard, 3-Phosphoshikimic acid lithium salt
UOM: 1 * 10 mg
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Supelco® Organic Reference Standard, (±)-2,4-Dihydroxybutyric acid lithium salt

Proveedor: Merck
Descripción: Organic Standard, (±)-2,4-Dihydroxybutyric acid lithium salt

Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
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