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Anti-MVP Mouse Monoclonal Antibody (Purified) [clone: 1014]

Proveedor: Biotium
Descripción: Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.

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Anti-PECAM1 Mouse Monoclonal Antibody (Purified) [clone: C31.7]

Proveedor: Biotium
Descripción: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

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Anti-BrdU Mouse Monoclonal Antibody (Purified) [clone: MoBu-1]

Proveedor: Biotium
Descripción: This antibody reacts with Bromodeoxyuridine (BrdU) in single stranded DNA (produced by partial denaturation of double stranded DNA), BrdU coupled to a protein carrier, as well as free BrdU. BrdU is a thymidine analog, incorporated into cell nuclei during DNA synthesis prior to mitosis. Antibody to BrdU is helpful in detecting S-phase cells, providing useful information on the aggressiveness of tumors.

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Anti-EGFR Mouse Monoclonal Antibody (Purified) [clone: H9B4]

Proveedor: Biotium
Descripción: This MAb reacts with a cytoplasmic domain of EGFR. EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin & epiregulin.

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Anti-PTPRC Mouse Monoclonal Antibody (Purified) [clone: 2B11]

Proveedor: Biotium
Descripción: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

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Anti-CALD1 Mouse Monoclonal Antibody (Purified) [clone: h-CALD]

Proveedor: Biotium
Descripción: Recognizes a protein of 150 kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.

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Anti-ALPI Mouse Monoclonal Antibody (Purified) [clone: V17.1]

Proveedor: Biotium
Descripción: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Product Image-MFLX30492-32

PrimeLock® High-Purity PFA Fittings, NPT(M) Straight Adapters

Numero del catalogo: (MFLX30492-32)
Proveedor: Avantor Fluid Handling
Descripción: Ultra-clean and reliable fittings for highly critical and corrosive chemicals.
UOM: 1 * 1 UN

2 month warranty


Product Image-ACRO328400001

Okadaic acid sodium salt 98%, grado alta pureza

Numero del catalogo: (ACRO328400001)
Proveedor: Thermo Fisher Scientific
Descripción: Okadaic acid sodium salt 98%, grado alta pureza
UOM: 1 * 0,1 mg

FDS


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Gas clean purification system

Numero del catalogo: (HEWLCP17989)
Proveedor: Agilent
Descripción: The Gas Clean Filter System delivers clean gases, reducing the risks of column damage, sensitivity loss, and instrument downtime.
UOM: 1 * 1 UN
Product Image-ANTIA79854-96

Mouse Furin ELISA Kit

Numero del catalogo: (ANTIA79854-96)
Proveedor: ANTIBODIES.COM
Descripción: Mouse Furin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse Furin in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Product Image-ANTIA310764-96

Human Furin ELISA Kit

Numero del catalogo: (ANTIA310764-96)
Proveedor: ANTIBODIES.COM
Descripción: Human Furin ELISA kit is a 90 minutes sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i><i>in vitro</i></i> quantitative determination of human Furin in serum, plasma, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Product Image-ANTIA78432-96

Human Pyrin ELISA Kit

Numero del catalogo: (ANTIA78432-96)
Proveedor: ANTIBODIES.COM
Descripción: Human Pyrin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Pyrin in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Product Image-BIRBORB96801-96

Human furin ELISA kit

Numero del catalogo: (BIRBORB96801-96)
Proveedor: Biorbyt
Descripción: Human Furin ELISA Kit for the quantitative detection of human furin.
UOM: 1 * 96 Tests

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-BELC5638-01920

Microscope slides with printed rings

Numero del catalogo: (BELC5638-01920)
Proveedor: BELLCO GLASS
Descripción: These microscopy slides with three printed rings allow for counting bacteria by spreading a known volume of solution over a known area for the calculation of bacteria per sample.
UOM: 1 * 144 UN

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-BSBTPB9182

Anti-Furin Polyclonal Antibody

Numero del catalogo: (BSBTPB9182)
Proveedor: Boster Bio
Descripción: Polyclonal antibody for FURIN detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. FURIN information: Molecular Weight: 86678 MW; Subcellular Localization: Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Shuttles between the trans-Golgi network and the cell surface. Propeptide cleavage is a prerequisite for exit of furin molecules out of the endoplasmic reticulum (ER). A second cleavage within the propeptide occurs in the trans Golgi network (TGN), followed by the release of the propeptide and the activation of furin; Tissue Specificity: Seems to be expressed ubiquitously.
UOM: 1 * 100 µG
Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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