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Product Image-ENZOBMLDG1000050

(±)1,2-Didecanoylglycerol (10:0) ≥98% (by TLC), white solid

Descripción: PKC activator.
Numero del catalogo: ENZOBMLDG1000050
UOM: 1 * 50 mg
Proveedor: ENZO LIFE SCIENCES
Image Unavailable-BNUB0235-100

Anti-ABO Mouse Monoclonal Antibody (Purified) [clone: HE-14]

Descripción: This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. It is also reactive with the immuno-dominant A trisaccharide. Blood group antigen expression in human colon cancer was studied by means of two monoclonal antibodies of broad anti-A (HE-14) and anti-type 3 and type 4 chain-based A and H (HE-10) specificity. These antigens were proved to re-appear in tumors of the distal colon, the HE-10 antibody reacting more frequently (9 out of 12 samples) than HE-14 (5 out of 12 samples) and frequently with supra-nuclear staining of the cytoplasm probably in those places of the Golgi apparatus where carbohydrate antigens are synthesized. This staining pattern is characteristic of HE-10 in normal colonic mucosa as well. With HE-14, staining was often absent in less differentiated tumors, while HE-10 did react in such tumors. In some cases, these two antibodies gave different staining patterns in parallel sections from the same tissue sample, primarily at the cellular level. Three out of 12 cases showed blood group antigen expression in the mucosa of the distal colon adjacent to the tumor only when HE-10 Ab was used.
Numero del catalogo: BNUB0235-100
UOM: 1 * 100 µl
Proveedor: Biotium
Image Unavailable-BNUM0235-50

Anti-ABO Mouse Monoclonal Antibody (Purified, BSA-free) [clone: HE-14]

Descripción: This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. It is also reactive with the immuno-dominant A trisaccharide. Blood group antigen expression in human colon cancer was studied by means of two monoclonal antibodies of broad anti-A (HE-14) and anti-type 3 and type 4 chain-based A and H (HE-10) specificity. These antigens were proved to re-appear in tumors of the distal colon, the HE-10 antibody reacting more frequently (9 out of 12 samples) than HE-14 (5 out of 12 samples) and frequently with supra-nuclear staining of the cytoplasm probably in those places of the Golgi apparatus where carbohydrate antigens are synthesized. This staining pattern is characteristic of HE-10 in normal colonic mucosa as well. With HE-14, staining was often absent in less differentiated tumors, while HE-10 did react in such tumors. In some cases, these two antibodies gave different staining patterns in parallel sections from the same tissue sample, primarily at the cellular level. Three out of 12 cases showed blood group antigen expression in the mucosa of the distal colon adjacent to the tumor only when HE-10 Ab was used.
Numero del catalogo: BNUM0235-50
UOM: 1 * 50 µl
Proveedor: Biotium
Image Unavailable-CAYM15632-50

7-Ethyl-10-hydroxycamptothecin ≥98%

Descripción: SN-38 is the active metabolite of irinotecan, a derivative of the alkaloid camptothecin and acts as a potent inhibitor of DNA topoisomerase I. SN-38 is a more potent topopisomerase I inhibitor and more cytotoxic to HT-29 colon cancer cells (IC<sub>50</sub> = 8.8 nM) compared to irinotecan (IC<sub>50</sub> >100 nM).
Numero del catalogo: CAYM15632-50
UOM: 1 * 50 mg
Proveedor: Cayman Chemical
Image Unavailable-PRSI33-375

Anti-ABO Mouse Monoclonal Antibody [clone: HE-14]

Descripción: This antibody recognises human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. It is also reactive with the immuno-dominant A trisaccharide. Blood group antigen expression in human colon cancer was studied by means of two monoclonal antibodies of broad anti-A (HE-14) and anti-type 3 and type 4 chain-based A and H (HE-10) specificity. These antigens were proved to re-appear in tumors of the distal colon, the HE-10 antibody reacting more frequently (9 out of 12 samples) than HE-14 (5 out of 12 samples) and frequently with supra-nuclear staining of the cytoplasm probably in those places of the Golgi apparatus where carbohydrate antigens are synthesised. This staining pattern is characteristic of HE-10 in normal colonic mucosa as well. With HE-14, staining was often absent in less differentiated tumors, while HE-10 did react in such tumors. In some cases, these two antibodies gave different staining patterns in parallel sections from the same tissue sample, primarily at the cellular level. Three out of 12 cases showed blood group antigen expression in the mucosa of the distal colon adjacent to the tumor only when HE-10 mAb was used.
Numero del catalogo: PRSI33-375
UOM: 1 * 100 µG
Proveedor: ProSci Inc.

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Image Unavailable-BOSSBS-13754R

Anti-Claudin 12 Rabbit Polyclonal Antibody

Descripción: The claudin superfamily consists of many structurally related proteins that are important structural and functional components of tight junctions. Claudin-12, also known as CLDN12, is a 244 amino acid multi-pass membrane protein that is expressed in the brain, duodenum, jejunum, ileum, and colon. Claudin-12 localizes to cell junctions and may be involved in tight junction integrity by regulating hyperammonemia. Ammonia can alter brain capillary endothelial cell gene expression and transporter function. Claudin-12 is upregulated in enterocytes through vitamin D receptors which strongly suggest that claudin-12 forms paracellular Ca(2+) channels in intestinal epithelia and may be critical for vitamin D-dependent calcium homeostasis.
Numero del catalogo: BOSSBS-13754R
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-8270R

Anti-GIMAP4 Rabbit Polyclonal Antibody

Descripción: Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.Tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
Numero del catalogo: BOSSBS-8270R
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-8270R-CY5

Anti-GIMAP4 Rabbit Polyclonal Antibody (Cy5®)

Descripción: Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.Tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
Numero del catalogo: BOSSBS-8270R-CY5
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-8270R-CY3

Anti-GIMAP4 Rabbit Polyclonal Antibody (Cy3®)

Descripción: Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.Tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
Numero del catalogo: BOSSBS-8270R-CY3
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-8270R-CY7

Anti-GIMAP4 Rabbit Polyclonal Antibody (Cy7®)

Descripción: Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.Tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
Numero del catalogo: BOSSBS-8270R-CY7
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-8270R-A680

Anti-GIMAP4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Descripción: Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.Tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
Numero del catalogo: BOSSBS-8270R-A680
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-8270R-A488

Anti-GIMAP4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Descripción: Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.Tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
Numero del catalogo: BOSSBS-8270R-A488
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-8270R-HRP

Anti-GIMAP4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Descripción: Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.Tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
Numero del catalogo: BOSSBS-8270R-HRP
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-12163R

Anti-CAPS2 Rabbit Polyclonal Antibody

Descripción: CAPS2 is a 557 amino acid calcium-binding protein that is abundantly expressed, with highest expression found in placenta, testis, colon, lung and brain. CAPS2 contains three EF-hand domains and exists as three alternatively spliced isoforms. Suggested to play a role in large dense-core vesicle (LDCV) exocytosis, CAPS2 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Numero del catalogo: BOSSBS-12163R
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-12163R-A680

Anti-Calcyphosine 2/CAPS2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Descripción: CAPS2 is a 557 amino acid calcium-binding protein that is abundantly expressed, with highest expression found in placenta, testis, colon, lung and brain. CAPS2 contains three EF-hand domains and exists as three alternatively spliced isoforms. Suggested to play a role in large dense-core vesicle (LDCV) exocytosis, CAPS2 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Numero del catalogo: BOSSBS-12163R-A680
UOM: 1 * 100 µl
Proveedor: Bioss
Image Unavailable-BOSSBS-12163R-HRP

Anti-CAPS2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Descripción: CAPS2 is a 557 amino acid calcium-binding protein that is abundantly expressed, with highest expression found in placenta, testis, colon, lung and brain. CAPS2 contains three EF-hand domains and exists as three alternatively spliced isoforms. Suggested to play a role in large dense-core vesicle (LDCV) exocytosis, CAPS2 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Numero del catalogo: BOSSBS-12163R-HRP
UOM: 1 * 100 µl
Proveedor: Bioss
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