Esta buscando: 1-Butilpiridinio+bromuro

Numero del catalogo: (BOSSBS-3348R-CY5)

Proveedor: Bioss

Descripción: PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (1.01005.1000)

Proveedor: MERCK PRODUCTION CHEMICALS

Descripción: 1,1,1-Tricloro-2-metil-2-propanol hemihidrato NF, BP, Ph. Eur., JP, SAFC®

UOM: 1 * 1 kg

FDS Promoción

Numero del catalogo: (91114.001)

Proveedor: VWR Chemicals

Descripción: A standard mixture, typically used for food testing, containing the following components: 100 ug/ml each of Aldrin [CAS:309-00-2] ; Alpha-HCH [CAS:319-84-6] ; Beta-HCH [CAS:319-85-7] ; Delta-HCH [CAS:319-86-8] ; Gamma-HCH (Lindane) [CAS:58-89-9] ; Chlorbenside [CAS:103-17-3] ; cis-Chlordane [CAS:5103-71-9] ; trans-Chlordane [CAS:5103-74-2] ; Chlorfenson [CAS:80-33-1] ; Chloroneb [CAS:2675-77-6] ; 2,4'-DDD [CAS:53-19-0] ; 4,4'-DDD (TDE) [CAS:72-54-8] ; 2,4'-DDE [CAS:3424-82-6] ; 4,4'-DDE [CAS:72-55-9] ; 2,4'-DDT [CAS:789-02-6] ; 4,4'-DDT [CAS:50-29-3] ; 4,4'-Dichlorobenzophenone [CAS:90-98-2] ; Dieldrin [CAS:60-57-1] ; Endosulfan-alpha [CAS:959-98-8] ; Endosulfan-beta [CAS:33213-65-9] ; Endosulfan-ether [CAS:3369-52-6] ; Endosulfan-total (sulfate) [CAS:1031-07-8] ; Endrin [CAS:72-20-8] ; Endrin aldehyde [CAS:7421-93-4] ; Endrin ketone [CAS:53494-70-5] ; Perthane [CAS:72-56-0] ; Fenson [CAS:80-38-6] ; Heptachlor [CAS:76-44-8] ; Heptachlor-exo-epoxide [CAS:1024-57-3] ; Hexachlorobenzene [CAS:118-74-1] ; Isodrin [CAS:465-73-6] ; o,p'-Methoxychlor-olefin [CAS:30667-99-3] ; 4,4'-Methoxychlor olefin [CAS:2132-70-9] ; Mirex [CAS:2385-85-5] ; cis-Nonachlor [CAS:5103-73-1] ; trans-Nonachlor [CAS:39765-80-5] ; Pentachloroanisole [CAS:1825-21-4] ; Pentachlorobenzene [CAS:608-93-5] ; Methyl-pentachlorophenyl sulfide [CAS:1825-19-0] ; Tetradifon [CAS:116-29-0] in Toluene

UOM: 1 * 1 mL

FDS Certificados Promoción

Numero del catalogo: (BOSSBS-3348R-CY3)

Proveedor: Bioss

Descripción: PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-3348R)

Proveedor: Bioss

Descripción: PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (AATB14014)

Proveedor: AAT BIOQUEST

Descripción: 4-Methylumbelliferyl-beta-D-glucoside is a fluorogenic MU substrate for detecting glucosidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer.

UOM: 1 * 25 mg

Promoción

Numero del catalogo: (BOSSBS-4098R-CY3)

Proveedor: Bioss

Descripción: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-6144R-A680)

Proveedor: Bioss

Descripción: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilising properties and the half-life of their target mRNAs.

UOM: 1 * 100 µl

Promoción

Proveedor: Thermo Fisher Scientific

Descripción: Harmaline ≥98%

FDS Certificados

Numero del catalogo: (BOSSBS-3348R-A750)

Proveedor: Bioss

Descripción: PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-0483R-CY5.5)

Proveedor: Bioss

Descripción: Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-0483R-FITC)

Proveedor: Bioss

Descripción: Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.

UOM: 1 * 100 µl

Promoción

Proveedor: Spectrum Chemical

Descripción: Melamine statement (available upon request)
BSE/TSE statement (available upon request)
Allergen statement (available upon request)

Proveedor: Thermo Fisher Scientific

Descripción: 4-Methylumbelliferyl-β-D-glucopyranoside 99%

Certificados

Numero del catalogo: (BOSSBS-3348R-A350)

Proveedor: Bioss

Descripción: PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-0483R-CY5)

Proveedor: Bioss

Descripción: Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.

UOM: 1 * 100 µl

Promoción