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Product Image-PIER22105

Pierce™ PEGylated SMCC Crosslinkers, Heterobifunctional

Proveedor: Thermo Fisher Scientific
Descripción: Cross linkers are used for the identification of near-neighbour protein relationships and ligand-receptor interactions. Homobifunctional, amine-reactive NHS esters or imidates, and heterobifunctional, amine-reactive, photoactivatable phenyl azides are the most commonly used crosslinkers for these applications.

Product Image-AATB202

6-Carboxy-2',4,4',5',7,7'-hexachlorofluorescein succinimidyl ester (6-HEX SE) single isomer ≥90%

Numero del catalogo: (AATB202)
Proveedor: AAT BIOQUEST
Descripción: 6-HEX, SE is the amine-reactive succinimidyl ester of 6-HEX acid.
UOM: 1 * 5 mg
Product Image-RPN5661

Post-labelling reactive dye packs, CyDye™

Numero del catalogo: (RPN5661)
Proveedor: Cytiva
Descripción: CyDye™ Post-labelling reactive dye pack for the generation of highly fluorescent Cy3- and Cy5-labelled probes.
UOM: 1 * 1 KIT
Product Image-PIER26169

SDAD (NHS-SS-Diazirine) (succinimidyl 2-((4,4'-azipentanamido)ethyl)-1,3'-dithiopropionate), Pierce™

Numero del catalogo: (PIER26169)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce SDAD (NHS-SS-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 13.5Å spacer arm containing a cleavable disulfide bond separates the two photoreactive groups.
UOM: 1 * 50 mg
Image Unavailable-PIER20593

DSG (Disuccinimidyl glutarate), Pierce™

Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce DSG is a water-insoluble, homo-bifunctional N-hydroxysuccinimide ester (NHS-ester) crosslinker often used for conjugating radiolabeled ligands to cell-surface receptors. The NHS ester is the simplest and most commonly used reactive group for crosslinking and labeling proteins and peptides. NHS esters react with primary amines on the N-termini of peptides and the  amine of lysine residues, forming a stable, covalent amide bond and releasing the NHS group.

Product Image-PIER22298

BMPS (3-Maleimidopropionic acid N-hydroxysuccinimide ester), Pierce™

Numero del catalogo: (PIER22298)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce BMPS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (5.9 Å).
UOM: 1 * 50 mg
Product Image-PA13004

Amersham™ CyDye™ Value Packs (Bis-Reactive NHS Esters)

Proveedor: Cytiva
Descripción: Amersham™ CyDye™ fluors combine exceptional photostability with bright and intense signals, resulting in high sensitivity and a highly reproducible performance at a biologically suitable pH range of 3 to 10.

Product Image-PIER22311

MBS (N-Succinimidyl 3-maleimidobenzoate), Pierce™

Numero del catalogo: (PIER22311)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce MBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short aromatic spacer arm (7.3 angstroms).
UOM: 1 * 50 mg
Product Image-PIER22416

SMPB (N-Succinimidyl 4-(4-Maleimidophenyl)butyrate), Pierce™

Numero del catalogo: (PIER22416)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce SMPB is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length aromatic spacer arm (11.6 angstroms).
UOM: 1 * 50 mg
Product Image-PIER22349

SIA (N-Succinimidyl iodoacetate)

Numero del catalogo: (PIER22349)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce SIA is a very short (1.5 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.
UOM: 1 * 50 mg
Product Image-PIER22360

SMCC (N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate), Pierce™

Numero del catalogo: (PIER22360)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.
UOM: 1 * 50 mg

FDS Certificados


Image Unavailable-PIERA35394

SMCC (N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate), No-Weigh™ Format, Pierce™

Numero del catalogo: (PIERA35394)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce SMCC is a hetero-bifunctional crosslinker that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7–9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5–7.5 to form stable thioether bonds. In aqueous solutions, NHS ester hydrolytic degradation is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group, but will slowly hydrolyze and lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugations with these crosslinkers are usually performed at pH 7.2–7.5, with the NHS ester (amine-targeted) reacted before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.
UOM: 1 * 10 mg
Product Image-PIER26174

Sulpho-LC-SDA (Sulpho-NHS-LC-Diazirine) (Sulphosuccinimidyl 6-(4,4′-azipentanamido)hexanoate), Pierce™

Numero del catalogo: (PIER26174)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce Sulfo-LC-SDA (Sulfo-NHS-LC-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 12.5Å spacer arm separates the two photoreactive groups.
UOM: 1 * 50 mg
Product Image-PIER26175

Sulpho-SDAD (Sulpho-NHS-SS-Diazirine) (Sulphosuccinimidyl 2-[(4,4′-azipentanamido)ethyl]-1,3′-dithiopropionate], Pierce™

Numero del catalogo: (PIER26175)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce Sulfo-SDAD (Sulfo-NHS-SS-Diazirine) combines proven NHS-ester and diazirine-based photoreaction chemistries with conjugate amine-containing molecules with nearly any other functional group via long-wave UV-light activation. A 13.5Å spacer arm containing a cleavable disulfide bond separates the two photoreactive groups.
UOM: 1 * 50 mg
Product Image-PIER22312

Sulpho-MBS (3-Maleimidobenzoyl-N-hydroxysulphosuccinimide ester sodium salt), Pierce™

Numero del catalogo: (PIER22312)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce Sulfo-MBS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short aromatic spacer arm (7.3 angstroms).
UOM: 1 * 50 mg
Product Image-PIER22339

SBAP (Succinimidyl 3-(bromoacetamido)propionate), Pierce™

Numero del catalogo: (PIER22339)
Proveedor: Thermo Fisher Scientific
Descripción: Thermo Scientific Pierce SBAP is a short (6.2 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and bromoacetyl reactive groups.
UOM: 1 * 50 mg
Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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