Esta buscando: psmc5

Numero del catalogo: (USBIP9004-25B-HRP)

Proveedor: US Biological

Descripción: Anti-PRMT5 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

UOM: 1 * 200 µl

Promoción

Numero del catalogo: (BOSSBS-9365R-A555)

Proveedor: Bioss

Descripción: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-9365R-A350)

Proveedor: Bioss

Descripción: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-9366R-A647)

Proveedor: Bioss

Descripción: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-9367R-A750)

Proveedor: Bioss

Descripción: In eukaryotic cells, selective breakdown of cellular proteins is ensured by two distinct pathways, ubiquitination and degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome are formed by developmentally regulated alternative splicing, including Rpn10a through Rpn10e (also designated pUb-R2 through pUb-R5). The pUb-R2 subunit, originally identified as S5a, is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. p44S10 is a highly conserved proteasome regulatory subunit that is expressed in heart, liver, skeletal muscle and pancreas. In addition to normal tissue expression, p44S10 is also expressed in several melanoma cell lines, such as MCF-7, 451Lu and WM164. Since forced expression of p44S10 in radial growth phase melanoma cells results in an increase in cellular proliferation, p44S10 may represent a potential link between regulation of proteasome activity and tumor cell proliferation <i>in vivo</i>.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-0179R-A680)

Proveedor: Bioss

Descripción: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-9352R-A350)

Proveedor: Bioss

Descripción: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-9357R-FITC)

Proveedor: Bioss

Descripción: The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin dependent process in a non lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (BOSSBS-2787R-A647)

Proveedor: Bioss

Descripción: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (USBI040571-FITC)

Proveedor: US Biological

Descripción: Anti-PSME1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

UOM: 1 * 200 µl

Promoción

Numero del catalogo: (ABCAAB321258-100UL)

Proveedor: Abcam

Descripción: Anti-PSMD9 Rabbit Monoclonal Antibody [clone: EPR12947] (Alexa Fluor® 750)

UOM: 1 * 100 µl

New Product Promoción

Numero del catalogo: (USBIP9076-09C-PE)

Proveedor: US Biological

Descripción: Anti-PSMA7 Rabbit Polyclonal Antibody (PE (Phycoerythrin))

UOM: 1 * 200 µl

Promoción

Numero del catalogo: (ABCAAB314183-100UL)

Proveedor: Abcam

Descripción: Anti-PSME1 Rabbit Monoclonal Antibody [clone: 29D5]

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (ORIGTA321528)

Proveedor: OriGene

Descripción: Anti-PSMD3 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Promoción

Numero del catalogo: (USBI131942)

Proveedor: US Biological

Descripción: Anti-PSMA4 Mouse Monoclonal Antibody [clone: 2A10-E4]

UOM: 1 * 100 µG

Promoción

Numero del catalogo: (BOSSBS-9367R-A680)

Proveedor: Bioss

Descripción: In eukaryotic cells, selective breakdown of cellular proteins is ensured by two distinct pathways, ubiquitination and degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome are formed by developmentally regulated alternative splicing, including Rpn10a through Rpn10e (also designated pUb-R2 through pUb-R5). The pUb-R2 subunit, originally identified as S5a, is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. p44S10 is a highly conserved proteasome regulatory subunit that is expressed in heart, liver, skeletal muscle and pancreas. In addition to normal tissue expression, p44S10 is also expressed in several melanoma cell lines, such as MCF-7, 451Lu and WM164. Since forced expression of p44S10 in radial growth phase melanoma cells results in an increase in cellular proliferation, p44S10 may represent a potential link between regulation of proteasome activity and tumor cell proliferation <i>in vivo</i>.

UOM: 1 * 100 µl

Promoción