Esta buscando: Tonbo Biosciences

Numero del catalogo: (22-8067-M001)

Proveedor: Tonbo Biosciences

Descripción: Goat anti-Rabbit IgG (H&L) - Affinity Pure, Alkaline Phosphatase Conjugate

UOM: 1 * 1 mg

Promoción

Numero del catalogo: (72-8097-M001)

Proveedor: Tonbo Biosciences

Descripción: Donkey anti-Mouse IgG (H&L) - Affinity Pure, HRP Conjugate

UOM: 1 * 1 mg

Promoción

Numero del catalogo: (30-8117-M001)

Proveedor: Tonbo Biosciences

Descripción: Goat anti-Human IgA (alpha chain) - Affinity Pure, Biotin Conjugate, min x w/bovine, mouse, and rabbit serum proteins

UOM: 1 * 1 mg

Promoción

Proveedor: Tonbo Biosciences

Descripción: The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta2-domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The RM4-5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the RM4-5 antibody and an alternative antibody, Anti-Mouse CD4 clone GK1.5, will compete for binding, i.e. RM4-5 antibody is able to block GK1.5 antibody binding to cells. In contrast, RM4-5 antibody does not block the binding of Anti-Mouse CD4 clone RM4-4 to cells.

Numero del catalogo: (72-8104-M001)

Proveedor: Tonbo Biosciences

Descripción: Goat anti-Rat IgG (H&L) - Affinity Pure, HRP Conjugate

UOM: 1 * 1 mg

Promoción

Numero del catalogo: (35-8015-U500)

Proveedor: Tonbo Biosciences

Descripción: Goat anti-Human IgA (alpha chain), F(ab')2 Fragment - Affinity Pure, FITC Conjugate

UOM: 1 * 0,5 mg

Promoción

Numero del catalogo: (30-8020-U500)

Proveedor: Tonbo Biosciences

Descripción: Goat anti-Human IgA (alpha chain), F(ab)'2 Fragment - Affinity Pure, Biotin Conjugate

UOM: 1 * 0,5 mg

Promoción

Numero del catalogo: (70-8030-M002)

Proveedor: Tonbo Biosciences

Descripción: Goat anti-Human IgM (mu chain) - Affinity Pure, min x w/human IgA + IgG

UOM: 1 * 2 mg

Promoción

Numero del catalogo: (35-8065-M002)

Proveedor: Tonbo Biosciences

Descripción: Goat anti-Mouse IgM (mu chain) - Affinity Pure, FITC Conjugate

UOM: 1 * 2 mg

Promoción

Numero del catalogo: (35-8066-M002)

Proveedor: Tonbo Biosciences

Descripción: Goat anti-Mouse IgM (mu chain) - Affinity Pure, FITC Conjugate, min x w/human IgG or serum proteins

UOM: 1 * 2 mg

Promoción

Numero del catalogo: (70-8042-M002)

Proveedor: Tonbo Biosciences

Descripción: Goat anti-Mouse IgG (H&L) - Affinity Pure

UOM: 1 * 2 mg

Promoción

Proveedor: Tonbo Biosciences

Descripción: The 17A2 antibody reacts with the mouse CD3 complex, comprised of CD3 epsilon, CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Proveedor: Tonbo Biosciences

Descripción: The Human Basic T Lymphocyte backbone panel is a four-color combination of anti-human antibodies. This panel can serve as a backbone for identifying the major T cell subsets, and leaves room for additional drop-in markers, if desired. Violet laser (405 nm) required for detection of CD4 violetFluorTM 450.

Proveedor: Tonbo Biosciences

Descripción: The PC61.5 antibody is specific for mouse CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Expression of CD25 varies during developmental stages of T and B cells, is induced on activated mature T and B cells, and is present on subsets of dendritic cells. CD25 signaling as part of the IL-2 receptor complex triggers T cell activation and proliferation, as well as modulating the differentiation and function of Th17 cells, T regulatory (Treg) cells, and dendritic cells. The PC61.5 antibody is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used to distinguish Treg cells from native or conventional T cells which are CD25-. This clone has also been reported for depletion of Treg cells in vivo (use format suitable for functional assays).

Proveedor: Tonbo Biosciences

Descripción: The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.

Proveedor: Tonbo Biosciences

Descripción: The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.