Anti-ESR1 Mouse Monoclonal Antibody [clone: ER505]

Proveedor: ProSci Inc.
33-126
PRSI33-126EA 0 EUR
PRSI33-126
Anti-ESR1 Mouse Monoclonal Antibody [clone: ER505]
Anticuerpos
Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. It is found in two forms, alpha and beta. Both forms are widely expressed, however, alpha is the predominant form in endometrium and breast cancer cells, and beta is more highly expressed in brain, kidney, heart, lung and bone. Activated Estrogen receptor dimerizes and forms both homo- and heterodimers. ER contains five domains: A-F. The A and B domain are able to weakly activate ER in the absence of ligand. The C domain binds DNA and the E domain contains the ligand binding site. Presence ofMore Product Information
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