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Numero del catalogo: (65-0289-T100)

Proveedor: Tonbo Biosciences

Descripción: The CD28.2 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

UOM: 1 * 100 Tests

Promoción

Proveedor: Tonbo Biosciences

Descripción: The OKT8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Proveedor: Tonbo Biosciences

Descripción: The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte "rolling" on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research. The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.

Numero del catalogo: (AATB2654)

Proveedor: AAT BIOQUEST

Descripción: PerCP (Peridinin-chlorophyll-protein complex) is isolated from Dinophyceae sp.

UOM: 1 * 1 mg

New Product Promoción

Numero del catalogo: (91-0003-U025)

Proveedor: Tonbo Biosciences

Descripción: The Mouse Myeloid Precursor backbone panel is a five-color combination of seven anti-mouse antibodies. This panel can serve as a backbone to identify various myeloid precursor populations, and leaves room for GFP or additional drop-in markers, if desired. The CD3e, CD19 and CD45R/B220 positive cells are gated together to exclude mature T and B cells. Violet laser (405 nm) required for detection of CD11b violetFluorTM 450. Hosts: Rat, Armenian Hamster

UOM: 1 * 25 µG

Promoción

Numero del catalogo: (AATB2590)

Proveedor: AAT BIOQUEST

Descripción: PerCP (Peridinin-chlorophyll-protein complex) is isolated from Dinophyceae sp.

UOM: 1 * 1 mg

Promoción

Proveedor: Tonbo Biosciences

Descripción: The SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.

Proveedor: Tonbo Biosciences

Descripción: The SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells. The SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.

Numero del catalogo: (AATB2723)

Proveedor: AAT BIOQUEST

Descripción: PerCP (Peridinin-chlorophyll-protein complex) is isolated from Dinophyceae sp.

UOM: 1 * 1 mg

New Product Promoción

Numero del catalogo: (AATB2652)

Proveedor: AAT BIOQUEST

Descripción: PerCP (Peridinin-chlorophyll-protein complex) is isolated from Dinophyceae sp.

UOM: 1 * 1 mg

New Product Promoción

Numero del catalogo: (AATB2655)

Proveedor: AAT BIOQUEST

Descripción: PerCP (Peridinin-chlorophyll-protein complex) is isolated from Dinophyceae sp.

UOM: 1 * 1 mg

New Product Promoción

Numero del catalogo: (AATB2595)

Proveedor: AAT BIOQUEST

Descripción: PerCP (Peridinin-chlorophyll-protein complex) is isolated from Dinophyceae sp.

UOM: 1 * 1 mg

Promoción

Numero del catalogo: (AATB2724)

Proveedor: AAT BIOQUEST

Descripción: PerCP-Cy5.5 is a popular tandem color used in flow cytometry.

UOM: 1 * 1 mg

New Product Promoción

Numero del catalogo: (AATB2650)

Proveedor: AAT BIOQUEST

Descripción: PerCP (Peridinin-chlorophyll-protein complex) is isolated from <i>Dinophyceae</i> sp.

UOM: 1 * 1 mg

Promoción

Numero del catalogo: (AATB2651)

Proveedor: AAT BIOQUEST

Descripción: PerCP (Peridinin-chlorophyll-protein complex) is isolated from Dinophyceae sp.

UOM: 1 * 1 mg

New Product Promoción

Numero del catalogo: (AATB2725)

Proveedor: AAT BIOQUEST

Descripción: PerCP-Cy7 is a popular tandem color used in flow cytometry.

UOM: 1 * 1 mg

New Product Promoción