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Image Unavailable-BOSSBS-12324R-A750

Anti-PTCHD2/DISP3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numero del catalogo: (BOSSBS-12324R-A750)
Proveedor: Bioss
Descripción: PTCHD2 is a 1392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6764R

Anti-NPC1 Rabbit Polyclonal Antibody

Numero del catalogo: (BOSSBS-6764R)
Proveedor: Bioss
Descripción: This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009].
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-5046R-A350

Anti-CYP46A1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Numero del catalogo: (BOSSBS-5046R-A350)
Proveedor: Bioss
Descripción: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3694R-CY5.5

Anti-CETP Rabbit Polyclonal Antibody (Cy5.5®)

Numero del catalogo: (BOSSBS-3694R-CY5.5)
Proveedor: Bioss
Descripción: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2399R-CY7

Anti-CYP7A1 Rabbit Polyclonal Antibody (Cy7®)

Numero del catalogo: (BOSSBS-2399R-CY7)
Proveedor: Bioss
Descripción: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2399R-CY5

Anti-CYP7A1 Rabbit Polyclonal Antibody (Cy5®)

Numero del catalogo: (BOSSBS-2399R-CY5)
Proveedor: Bioss
Descripción: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2399R-CY3

Anti-CYP7A1 Rabbit Polyclonal Antibody (Cy3®)

Numero del catalogo: (BOSSBS-2399R-CY3)
Proveedor: Bioss
Descripción: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2399R-CY5.5

Anti-CYP7A1 Rabbit Polyclonal Antibody (Cy5.5®)

Numero del catalogo: (BOSSBS-2399R-CY5.5)
Proveedor: Bioss
Descripción: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl
Image Unavailable-A0807.0100

Colesterol

Numero del catalogo: (A0807.0100)
Proveedor: PanReac AppliChem
Descripción: Colesterol
UOM: 1 * 100 g
Image Unavailable-BOSSBS-2399R-HRP

Anti-CYP7A1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Numero del catalogo: (BOSSBS-2399R-HRP)
Proveedor: Bioss
Descripción: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2399R-A750

Anti-CYP7A1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Numero del catalogo: (BOSSBS-2399R-A750)
Proveedor: Bioss
Descripción: Catalyses a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5046R

Anti-CYP46 Rabbit Polyclonal Antibody

Numero del catalogo: (BOSSBS-5046R)
Proveedor: Bioss
Descripción: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5051R-CY7

Anti-CYP46A1 Rabbit Polyclonal Antibody (Cy7®)

Numero del catalogo: (BOSSBS-5051R-CY7)
Proveedor: Bioss
Descripción: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5051R-CY5

Anti-CYP46A1 Rabbit Polyclonal Antibody (Cy5®)

Numero del catalogo: (BOSSBS-5051R-CY5)
Proveedor: Bioss
Descripción: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5051R-CY5.5

Anti-CYP46A1 Rabbit Polyclonal Antibody (Cy5.5®)

Numero del catalogo: (BOSSBS-5051R-CY5.5)
Proveedor: Bioss
Descripción: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5046R-CY5

Anti-CYP46A1 Rabbit Polyclonal Antibody (Cy5®)

Numero del catalogo: (BOSSBS-5046R-CY5)
Proveedor: Bioss
Descripción: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl
Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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