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Numero del catalogo: (BOSSBS-8682R-A647)
Proveedor: Bioss
Descripción: The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade. There are 2 members of the Epac family, Epac1 and Epac 2. Both proteins are multidomain proteins containing an autoinhibitory cAMP-binding domain that inhibits the catalytic region and a DEP domain (dishevelled, Egl-10 and pleckstrin homology domain) targeting the membrane anchors. EPAC2 has an additional cAMP-binding site in its N-terminus that binds cAMP with low affinity. EPAC1 mRNA is broadly expressed, with particularly high levels occurring in the thyroid, ovary, kidney and certain brain regions, whereas expression of EPAC2 mRNA appears to be restricted to the brain and adrenal glands. Epac 1 and Epac 2 also interact with light chain 2 (LC2) or MAP1A that serves as a scaffolding structure to stabilize the signal transduction complex. The Epac 1-selective were generated against unique antigenic sequences form near N-terminus and between RasGEFN and Ras GEF domains. The to Epac 1are affinity purified over immobilized antigen based chromatography.
UOM: 1 * 100 µl


Numero del catalogo: (BOSSBS-8682R-A750)
Proveedor: Bioss
Descripción: The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade. There are 2 members of the Epac family, Epac1 and Epac 2. Both proteins are multidomain proteins containing an autoinhibitory cAMP-binding domain that inhibits the catalytic region and a DEP domain (dishevelled, Egl-10 and pleckstrin homology domain) targeting the membrane anchors. EPAC2 has an additional cAMP-binding site in its N-terminus that binds cAMP with low affinity. EPAC1 mRNA is broadly expressed, with particularly high levels occurring in the thyroid, ovary, kidney and certain brain regions, whereas expression of EPAC2 mRNA appears to be restricted to the brain and adrenal glands. Epac 1 and Epac 2 also interact with light chain 2 (LC2) or MAP1A that serves as a scaffolding structure to stabilise the signal transduction complex. The Epac 1-selective were generated against unique antigenic sequences form near N-terminus and between RasGEFN and Ras GEF domains. The to Epac 1are affinity purified over immobilised antigen based chromatography.
UOM: 1 * 100 µl


Numero del catalogo: (BOSSBS-8682R-CY5)
Proveedor: Bioss
Descripción: The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade. There are 2 members of the Epac family, Epac1 and Epac 2. Both proteins are multidomain proteins containing an autoinhibitory cAMP-binding domain that inhibits the catalytic region and a DEP domain (dishevelled, Egl-10 and pleckstrin homology domain) targeting the membrane anchors. EPAC2 has an additional cAMP-binding site in its N-terminus that binds cAMP with low affinity. EPAC1 mRNA is broadly expressed, with particularly high levels occurring in the thyroid, ovary, kidney and certain brain regions, whereas expression of EPAC2 mRNA appears to be restricted to the brain and adrenal glands. Epac 1 and Epac 2 also interact with light chain 2 (LC2) or MAP1A that serves as a scaffolding structure to stabilize the signal transduction complex. The Epac 1-selective were generated against unique antigenic sequences form near N-terminus and between RasGEFN and Ras GEF domains. The to Epac 1are affinity purified over immobilized antigen based chromatography.
UOM: 1 * 100 µl


Proveedor: Cytiva
Descripción: The appearance of streaks that distort 2-D electrophoresis maps is a common problem, occurring most frequently when running gels that contain regions greater than pH 7,0. Increased sample load, increased length of the IPG strip, or using a narrower pH gradient worsens the problem. Extra spots on 2-D gels, caused by non specific oxidation of proteins, is another difficulty encountered when running gels containing basic regions. Both streaking and non specific oxidation result in poorly resolved protein patterns and reduced reproducibility between electrophoresis runs.

Proveedor: OZ BIOSCIENCES
Descripción: GeneBlaster™ transfection boosters are an innovative and efficient solution to improving gene expression levels. GeneBlaster™ kits are a set of chemicals designed to get higher and longer transgene expression levels.

Proveedor: OZ BIOSCIENCES
Descripción: FluoMag™ reagents are fluorescently-labeled magnetic nanoparticles for Magnetofection™ applications. FluoMag™ transfection reagents are as efficient as their non labelled counterparts and allow visualisation of the nanoparticles <i>in vitro</i> during experiments.

Numero del catalogo: (1.09011.0500)
Proveedor: Merck
Descripción: Determinación de sales de amonio/nitrógeno utilizando materiales que contienen mercurio.
UOM: 1 * 500 mL

FDS


Proveedor: OZ BIOSCIENCES
Descripción: HYPE-293™ transfection kits are dedicated to achieving high yield protein expression in HEK-293, 293-S, 293-F, or any 293-related cells grown in suspension.

Proveedor: Thermo Fisher Scientific
Descripción: Pierce™ Recombinant Protein A is useful as the basis for preparing various kinds of probes or affinity media for detection or purification of rabbit and human antibodies, especially IgG isotypes, in immunoassays and antibody purification protocols.

Proveedor: Thermo Fisher Scientific
Descripción: TurboFect™ reagent an easy to use, non-immunogenic transfection reagent for delivery of DNA plasmids and expression vectors into eukaryotic cells.

Numero del catalogo: (87787.290)
Proveedor: VWR Chemicals
Descripción: Reactivo de Biuret en solución Reag. Ph. Eur.
UOM: 1 * 1 L

FDS Certificados


Proveedor: Merck
Descripción: Determinación de sales de amonio/nitrógeno utilizando materiales que contienen mercurio.
Proveedor: VWR Chemicals
Descripción: Potasio hidrogenocarbonato, grado reactivo

FDS

Numero del catalogo: (PIER88944)
Proveedor: Thermo Fisher Scientific
Descripción: An optimized buffer for aldehyde-hydrazide and aldehyde-alkoxyamine coupling reactions.
UOM: 1 * 100 mL


Numero del catalogo: (786-428)
Proveedor: G-Biosciences
Descripción: Adenine deaminase converts adenine to hypoxanthine. It is a highly purified recombinant enzyme protein supplied at a 1 µM concentration.
UOM: 1 * 0,25 mL


Proveedor: OZ BIOSCIENCES
Descripción: 3D-Fect™ transfection reagent is specifically designed to directly transfect cells cultured in 3D scaffolds.

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El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
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El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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