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Numero del catalogo: (BOSSBS-2162R-CY7)
Proveedor: Bioss
Descripción: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
UOM: 1 * 100 µl


Numero del catalogo: (44651.AE)
Proveedor: Thermo Fisher Scientific
Descripción: Multi-Element Standard, 8 component standard, 100 µg/ml , Specpure®, Matriz: 5% HNO₃, Aplicación: Patrones ICP-MS
UOM: 1 * 100 mL

FDS Certificados


Numero del catalogo: (BOSSBS-5691R)
Proveedor: Bioss
Descripción: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
UOM: 1 * 100 µl


Numero del catalogo: (BOSSBS-13004R)
Proveedor: Bioss
Descripción: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity).
UOM: 1 * 100 µl


Numero del catalogo: (BOSSBS-5690R)
Proveedor: Bioss
Descripción: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
UOM: 1 * 100 µl


Numero del catalogo: (BOSSBS-5691R-CY7)
Proveedor: Bioss
Descripción: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
UOM: 1 * 100 µl


Numero del catalogo: (BOSSBS-5691R-FITC)
Proveedor: Bioss
Descripción: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
UOM: 1 * 100 µl


Numero del catalogo: (BOSSBS-9060R-CY5.5)
Proveedor: Bioss
Descripción: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity).
UOM: 1 * 100 µl


Numero del catalogo: (BOSSBS-5690R-A555)
Proveedor: Bioss
Descripción: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
UOM: 1 * 100 µl


Numero del catalogo: (620-3306)
Proveedor: Testo
Descripción: El testo 810 permite medir de forma simultánea la temperatura ambiente y la temperatura de las superficies sin contacto en un solo instrumento. Además, se incluye una pantalla con iluminación.
UOM: 1 * 1 UN


Proveedor: VWR Chemicals
Descripción: Estos patrones se pueden usar con cualquier medidor de punto de fusión. Se preparan con materia pura sin procesar. Los puntos de fusión se pueden determinar mediante un sistema calorímetro de barrido diferencial (DSC) de alta precisión que se calibra según la escala de temperatura internacional ITS-90.
Numero del catalogo: (BOSSBS-5691R-HRP)
Proveedor: Bioss
Descripción: A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
UOM: 1 * 100 µl


Proveedor: VWR Collection
Descripción: Las balanzas de precisión VWR® Professional son ideales para usar en una amplia gama de tareas de pesaje de laboratorio, están diseñadas para emplearse en entornos multi-usuario (cada perfil de usuario tiene protección de contrasñea). Estas balanzas interactivas con base de datos interna para almacenar datos y métodos de secado, ayudan a mejorar la eficiencia y productividad. Todos los modelos profesionales tienen una pantalla táctil de 5” con menú en iconos, teclado táctil qwerty y una bandeja de acero inoxidable. Los modelos están configurados para GLP, almacenaje de pesadas, proyectos y datos de indentificación de usuarios, así como fecha y hora. La información BPL puede también imprimirse con resultados, con disponibilidad de impreso estadístico incluso sin una impresora estadística.

Numero del catalogo: (BOSSBS-7877R-HRP)
Proveedor: Bioss
Descripción: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. Monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization and degradation in lysosomes. Ubiquitinates FGFR1, leading to receptor internalization and degradation in lysosomes. Promotes ubiquitination of RAPGEF2. According to PubMed:18562292 the direct link between NEDD4 and PTEN regulation through polyubiquitination described in PubMed:17218260 is questionable. Involved in ubiquitination of ERBB4 intracellular domain E4ICD. Involved in the budding of many viruses. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. Ubiquitinates TNK2 and regulates EGF-induced degradation of EGFR and TNF2. Involved in the ubiquitination of ebola virus VP40 protein and this ubiquitination plays a role in facilitating viral budding.
UOM: 1 * 100 µl


Proveedor: THERMO MATRIX TECHNOLOGIES
Descripción: Permanently attached, laser-etched 2D barcodes on the bottom of each tube allow you to scan and decode tubes at once without removing them from the rack and allow data to be associated with each tube.

Environmentally Preferable

Numero del catalogo: (BOSSBS-0676R-CY5)
Proveedor: Bioss
Descripción: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes SRC-dependent phosphorylation of the matrix protease MMP14 and its lysosomal degradation. FGFR4 signaling is down-regulated by receptor internalization and degradation; MMP14 promotes internalization and degradation of FGFR4. Mutations that lead to constitutive kinase activation or impair normal FGFR4 inactivation lead to aberrant signaling.
UOM: 1 * 100 µl


Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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