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Product Image-VELPA00000003

Accessories for magnetic hotplate stirrers, ARE/AREX 5 series

Proveedor: VELP SCIENTIFIC
Descripción: Agitadores, magnético con placa calefactora

Product Image-735-0353

Microplate readers, SpectraMax® Plus384

Proveedor: MOLECULAR DEVICES
Descripción: SpectraMax® Plus 384 microplate reader can run both standard spectrophotometer and microplate reader applications on the same instrument. SpectraMax® Plus 384 provides ultrafast, full spectral range detection for cuvettes, 96-well, and 384-well microplates, with the only temperature-independent method for pathlength correction. Temperature control and shaking included as standard.

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Zinc protoporphyrin ≥95% (by TLC)

Proveedor: ENZO LIFE SCIENCES
Descripción: Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter.

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BEC ammonium salt ≥95% (by TLC)

Proveedor: ENZO LIFE SCIENCES
Descripción: Slow-binding competitive inhibitor of arginase I (Ki=0.4-0.6µM & KD=2.22µM for recombinant rat liver arginase) and arginase II (Ki=0.31µM at pH 7.5 and 0.03µM at pH 9.5 for human recombinant type II arginase). Enhances NO-dependent smooth muscle relaxation in human penile corpus cavernosum tissue. Does not inhibit nitric oxide synthase (NOS) and may serve as a valuable reagent to probe the physiological relationship between arginase and NOS. Inhibitor of rat aortic smooth muscle cell proliferation.

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4-Bromo-A-23187 free acid ≥98% (by TLC, NMR) ionophore, for calcium determination

Numero del catalogo: (59006.)
Proveedor: Biotium
Descripción: Similar to A-23187, 4-Bromo A-23187 is used for in situ calibrations of fluorescent Ca2 indicators to equilibrate intracellular and extracellular calcium concentrations and to allow Mn2 to enter cells to quench indicator fluorescence. However, since 4-bromo A-23187 is nonfluorescent, it is preferred over the blue fluorescent A-23187 for calibrations of UV-excited Ca2 indicators such as Indo-1 and Fura-2 in order to keep background fluorescence to a minimum.
UOM: 1 * 1 mg
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5(6)-Carboxyfluorescein N-hydroxysuccinimide ester (5/6-FAM SE) ≥98% (by TLC)

Numero del catalogo: (90024.)
Proveedor: Biotium
Descripción: 5(6)-FAM SE (full name: 5-(and-6)-Carboxyfluorescein, succinimidyl ester mixed isomers) is an amine-reactive green fluorescent dye widely used for labeling proteins or other molecules that contain a primary or secondary aliphatic amine. The coupling reaction is usually carried out at pH 8-9.5. The amide linkage from the coupling reaction is much more stable than the thiourea linkage formed from the coupling of an amine and an isothiocyanate.
UOM: 1 * 100 mg
Image Unavailable-ENZOBMLSL2100050

D,L-threo-PDMP hydrochloride ≥98% (by TLC)

Proveedor: ENZO LIFE SCIENCES
Descripción: Blocks glucosylation of ceramide by inhibiting UDP-glucose:ceramide glucosyltransferase (glucosylceramide synthetase). Inhibits the expression of cell surface glycolipid antigens and inhibits the growth of cultured rabbit skin fibroblasts. Possesses antitumor activity and inhibits Lewis lung carcinoma cell metastasis in vitro. Useful tool for studying the effects of cellular glycosphingolipid depletion. Enhances the apoptotic response to ionizing radiation by enhancing the ceramide signal.

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Accessories for REVOLVE

Proveedor: DISCOVER ECHO
Descripción: Accessory for microscopes, Upright/inverted microscope, Revolve, El inserto de la platina de la placa de Petri tiene capacidad para 4 × 35 mm

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Palmitoylethanolamide ≥98% (by TLC)

Numero del catalogo: (ENZOBMLFA0180050)
Proveedor: ENZO LIFE SCIENCES
Descripción: Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.
UOM: 1 * 50 mg
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Nω-Methyl-L-arginine monoacetate ≥99% (by TLC)

Proveedor: ENZO LIFE SCIENCES
Descripción: Competitively inhibits the generation of NO from arginine and is a useful tool for inhibition of NO mediated effects. In vitro, L-NMMA inhibits relaxation of rat aorta rings induced by acetylcholine (IC50=9.5µM). In vivo, it causes a dose dependent increase in mean arterial blood pressure in anesthetized rats (EC50=16.7mg/kg).

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Xestospongin C ≥90% (by TLC)

Numero del catalogo: (ENZOBMLCA4090050)
Proveedor: ENZO LIFE SCIENCES
Descripción: Xestonspongin C is a structurally novel marine alkaloid isolated from the Okinawan sponge Xestospongia sp. It is a potent, cell-permeable inhibitor of IP3 receptor-mediated Ca²⁺ release (IC50 = 358 nM). However, since xestospongin C also inhibits voltage-dependent Ca²⁺ and K⁺ currents at concentrations similar to those which inhibit the IP3 receptor, it can only be regarded as a selective blocker of the IP3 receptor in permeabilized cells and not in cells with intact plasma membranes. Has vasodilatory properties.
UOM: 1 * 50 µG
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6-Carboxyfluorescein-N-succinimidyl ester (6-FAM SE) ≥99% (by TLC) amine-reactive fluorescent dye

Numero del catalogo: (90023.)
Proveedor: Biotium
Descripción: 6-FAM, SE (full name: 6-Carboxyfluorescein, succinimidyl ester, single isomer) is the amine-reactive form of 6-carboxyfluorescein single isomer.
6-FAM SE is an amine-reactive green fluorescent dye widely used for labeling oligonucleotides or other biomolecules that contain a primary or secondary aliphatic amine. The coupling reaction is usually carried out at pH 8-9.5.
UOM: 1 * 10 mg
Product Image-552-0273

TLC developing chambers

Numero del catalogo: (552-0273)
Proveedor: MACHEREY-NAGEL
Descripción: Mason jar shaped developing chambers for TLC application. Glass of hydrolytic category III, lid is made of PP with LDPE sealing disk.
UOM: 1 * 4 UN
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15-Deoxy-δ-12,14-prostaglandin J2 ≥97% (by TLC)

Proveedor: ENZO LIFE SCIENCES
Descripción: Prostaglandin D2 derived nuclear peroxisome proliferator-activated receptor γ (PPARγ) ligand. Induces apoptosis in a number of cell types including human lung cancer cells, synoviocytes and macrophages. Promotes differentiation of fibroblasts to adipocytes. Antiinflammatory activity. Inhibits angiogenesis. Prevents TNFα induced leptin increase in mice. TRPA1 agonist. Serious doubts as to the biological relevance of this prostaglandin have been raised. Endogenous levels seem to be too low to have any effect as a PPARγ ligand.

Product Image-444-0277

VWR®, Universal harness for microplate shakers and orbital mini shakers

Numero del catalogo: (444-0277)
Proveedor: VWR Collection
Descripción: Sujeción universal, fijaciones a la bandeja para asegurar placas de perfil bajo
UOM: 1 * 1 UN
Product Image-43001-0102

J.T.Baker®, Plate Medio

Proveedor: Avantor
Descripción: La placa de almacenamiento de PP de 96 pocillos con pocillos cónicos.

Environmentally Preferable

Consulta de precio
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
El stock para este material es limitada pero puede estar disponible en un almacén cerca de usted. Por favor, asegúrese de que ha iniciado sesión en la web para que el stock disponible se puede mostrar. Si el call sigue apareciendo y usted necesita ayuda, por favor llámenos al 902 222 897 o por email en webshop.es@avantorsciences.com.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta. Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto se trata de un artículo regulado sometido a normativa que restringe su venta.
Si procede, nos pondremos en contacto con usted para solicitarle la licencia o declaración de uso necesaria para poder proceder al suministro del producto.
Este producto ha sido bloqueado por su organización. Por favor, pónganse en contacto con su departamento de compras para obtener más información.
El producto original ya no está disponible. Su sustituto se muestra a continuación.
El producto(s) marcados con este símbolo están descatalogados - se venden hasta acabar stock. Pueden encontrar alternativas buscando con el número de catálogo VWR listado arriba. Si necesita más ayuda, por favor llame al Servicio de atención al cliente de VWR al 902.222.897.
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